| A | B |
| Secession | The formal withdrawal of a state from the Union. |
| Millard Fillmore | President Taylor's successor which quickly made it clear that he supported the compromise of 1850. |
| Underground Railroad | A system of routes along which runaway slaves were helped to escape to Canada. |
| Harriet Tubman | One of the most famous conductors on the Underground Railroad. |
| Harriet Beecher Stowe | Published Uncle Tom's Cabin in 1852. |
| Franklin Pierce | Elected president in 1852 when the Whig vote was split after nominating a pro-Northern candidate |
| James Buchanan | Democratic candidate who was elected president in 1856, who proved to be an indecisive leader |
| Dred Scott | Slave who appealed to the Supreme Court on the grounds that living in Illinois (a free state) had made him a free man |
| Abraham Lincoln | Republican challenger who raced for the U.S. Senate in 1858 against Democratic incumbent Douglas. |
| Jefferson Davis | Unanimously elected as President of the Confederate States of America |