| A | B |
|---|
| Allergic reaction that involves IgE antibodies attached to mast cells & basophils | Type I (anaphylaxis) |
| Systemic anaphylaxis--severe & life-threatening allergic reaction that involves widespread release of large amounts of histamine | Systemic anaphylaxis |
| Allergic reaction that involves release of relatively small amounts of histamine in limited areas | Local anaphylaxis |
| "Hay fever" would be this type of allergic reaction | Type I (local anaphylaxis) |
| A person is stung by a bee and has a violent reaction involving shortness of breath & a drop in blood pressure | Type I (systemic anaphylaxis) |
| Allergic reaction mediated by IgG or IgM antibodies and complement; cells are lysed or severely damaged | Type II (Cytotoxic) |
| Type of reaction to a transfusion of the wrong type of blood cells | Type II (Cytotoxic) |
| Allergic reaction that causes damage by accumulation of antigen-antibody complexes on the basement membranes of cells such as those that line blood vessels | Type III (Immune complex) reaction |
| Allergic reaction carried out by cytotoxic T cells instead of antibodies | Type IV (Delayed hypersensitivity) |
| The tuberculosis skin test is based on this type of allergic reaction | Type IV (Delayed hypersensitivity) |
| Autoimmune disease that results when antibodies made against a virus also react with proteins on body cells; cells are destroyed | Type I Autoimmunity |
| Autoimmune disease that might severely damage the heart following a viral infection | Type I Autoimmunity |
| Autoimmune disease that involves making antibodies that react with cell surface antigens. The cells are not destroyed but harm is still done. | Type II (cytotoxic) autoimmunity |
| Myasthenia gravis and Grave's disease are examples of this type of autoimmune disease | Type II (cytotoxic) |
| Antibodies are made and react with soluble antigens; immune complexes damage tissues | Type III (immune complex) autoimmune disease |
| Lupus and rheumatoid arthritis are examples of this type of autoimmune disease | Type III (immune complex) disease |
| Type of autoimmune disease that involves attack on cells by cytotoxic T cells | Type IV (cell-mediated) |
| Hashimoto's thyroiditis and Type I diabetes mellitus are examples of this type of autoimmune disease | Type IV (cell-mediated) |
