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Pharmacology and the EMT

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Review of pharmacology terminology used by the EMT

AB
pharmacologystudy of drugs and their effects on the human body
drugchemical agent used in the diagnosis, treatment, or prevention of disease
pharmacokineticsstudy of how drugs enter the body, reach their site of action, and are eventually eliminated
plantatropine (used in the treatment of heart blocks and bradycardia)
animalinsulin (extracted from the pancreas of cattle; used to treat diabetes)
mineralsodium bicarbonate (used to combat metabolic acidosis in the cardiac arrest patient)
syntheticlidocaine (used to treat cardiac dysrhythmia
Federal Food, Drug and Cosmetic Act of 1938requires packages to list the ingredients on foods and medications
Harrison Narcotic Actregulates the sale, importation, and manugacture of the opium plant and its derivatives
Controlled Substance Actregulates addictive drugs and defines the five schedules of controlled substances
Schedule Idrugs that have a high potential for abuse and have no accepted medical indications; example: heroin
Schedule IIdrugs that have a high potential for abuse, but also have accepted medical indications; examples: morphine and meperidine
Schedule IIIdrugs that have a reduced potential for abuse and accepcted medication indications; examples: acetaminophen with codeine
Schedule IVdrugs that have a low potential for abuse, but may cause a physical or psychological dependence; example: diazepam (Valium)
Schedule Vdrugs that have a low potential for abuse, yet contain small quantities of narcotics; examples: several types of cough medications
AMA drug evaluationsprovides drug information on groups of drugs, including their recommended dosages, side effects, indications, and contraindications
Physician's Desk Reference (PDR)compilation of manufacturers' drug information on the most current drugs on the market; contains photographs showing the actual size, shape, and color of many drugs; published yearly
drug insertsaccompany most drugs and supply the manufacturer recommendatons for use and other data
solutionspreparation in which the drugs are dissolved in a solvent, usually water; example: normal saline
tincturesdrug preparations in which the drug was extracted chemically with teh use of alcohol; example: tincture of iodine
suspensionsdrugs that do not dissolve in the solvent but are instead syspended in solution and will separate if not shaken frequently; example: amoxicillin
spiritsvolatile chemicals dissolved in alcohol, example: spirits of ammonia
emulsionsmixtures of an oil substance and a solvent; do not dissolve well and must be shaken before administration
elixirspreparation that contain a drug in alcohol with an added flavoring; example: Tylenol elixir
syrupsdrugs mixed with sugar, water, and flavoring, example: cough syrup
pillsdrugs shaped for easy swallowing; example: vitamins
powderdrugs in powder form, usually intened for mixing with another agent
capsulesgelatin containers filled with a drug powder; drug released as gelatin dissolves in the intestinal tract; example: dalmane
tabletspressed powder shaped in an easy-to-swallow form; example: aspirin
suppositoriesdrugs mised with a base that dissolves at body temperature; placed rectually or vaginally and absorbed by surrounding tissues
parenteral drugsmedications introducted through routes other than the digestive system, such as intravenous, intramuscular, and subcutaneous; the majority of EMS drugs
ampuleglass or plastic single-dose container that must be broken to obtain and use the drug
vialsingle or multi dose container that is sealed with a rubber cap; drug obtained by withdrawing it with a needle and a syringe
prefilled syringesingle-dose preloaded administration devide; can be used rapidly and is common in EMS
antagonismopposition between the actions of two or more drugs
bolussingle, often large, dose of medication
contraindicationsmedical or physiological reasons for not using a drug
cumulative actionresult of administering several small doses and achieving an increasing effect, usually due to buildup of the drug in the blood
depressantmedication that decreases a bodily function or activity
habituationpsychological or physiological dependence of a drug
hypersensitivityexaggerated reactivity to a drug or other foreign substance
idiosyncrasyindividual reaction to a drug that is very different from what is expected
indicationmedical condition for which the drug has a proven therapeutic value
potentiationenhancement of the effects on one drug by the administration of another
refractorycondition in which a drug fails to provide the therapeutic action desired for the patient
side effectsunavoidable and undersirable effects of a drug even in therapeutic doses
stimulantdrug that increases a bodily function or activity
synergismcombination of two drugs that together perform better than the sum of their isolated effects
therapeutic actionintended action of a drug
tolerancereduction in the obtained effects of a dosage of a drug over time, thus requiring larger dosages to achieve the same effect
absorptionentrance of the drug into the cardiovascular system
distributionmovement of the drug to the site wherer it is to be used
biotransformationconversion of the drug into its active form
eliminationwhithdrawal of the drug from the cardiovascular system and the removal of the drug from the body
blood barriermechanism that isolates the brain tissue from the bloodstream and selectively allows a limited number of compounds into the brain
parenteral routesintradermal, transdermal, subcutaneous, intramuscular, intravenous, endotracheal, intraocceus, inhalation, sublingual, intracardiac
enteral routessublingual, oral, rectal
factors that slow absorptionshock, acidosis, and peripheral vasconstriction dur to hypothermia
factors that enhance absorptionperipheral vasodilation, as caused by fever, hyperthermia, or other conditions that increase the blood supply at the injection site
metric systemsystem of measurement for mass, length, and volume; uses the decimal system (each unit is 10 times larger or 1/10 as large as the next); basic units include grams, meters, and liters.

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