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Glossary of Cardiovascular Terminology

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Large list of terms covering the cardiovascular system

AB
AbdomenThe area of the body between the bottom of the ribs and the top of the thighs.
Abdominal aortaThe portion of the aorta in the abdomen
AblationElimination or removal.
ACE (angiotensin-converting enzyme) inhibitorA drug that lowers blood pressure by interfering with the breakdown of a protein-like substance involved in blood pressure regulation.
AcetylcholineA type of chemical (called a neurotransmitter) that transmits messages among nerve cells and muscle cells.
AlveoliAir sacs in the lungs where oxygen and carbon dioxide are exchanged.
Amiodarone (Cordarone, Pacerone)A kind of medicine (called an antiarrhythmic), which is used to treat irregular heart rhythms such as atrial fibrillation and ventricular tachycardia. It works by regulating nerve impulses in your heart. Amiodarone is mainly given to patients who have not responded to other antiarrhythmic medicines.
AneurysmA sac-like protrusion from a blood vessel or the heart, resulting from a weakening of the vessel wall or heart muscle.
Angina or angina pectorisChest pain that occurs when diseased blood vessels restrict blood flow to the heart.
AngiographyAn x-ray technique that makes use of a dye injected into the coronary arteries to study blood circulation through the vessels. The test allows physicians to measure the degrees of obstruction to blood flow. Circulation through an artery is not seriously reduced until the inside diameter of the vessel is more than 75% obstructed.
AngioplastyA nonsurgical technique for treating diseased arteries by temporarily inflating a tiny balloon inside an artery.
AnnulusThe ring around a heart valve where the valve leaflet merges with the heart muscle.
AntiarrhythmicsMedicines that are used to treat patients who have irregular heart rhythms.
AnticoagulantAny drug that keeps blood from clotting; a blood thinner
AntihypertensiveAny drug or other therapy that lowers blood pressure
AortaThe largest artery in the body and the initial blood-supply vessel from the heart.
Aortic valveThe valve that regulates blood flow from the heart into the aorta
AphasiaThe inability to speak, write or understand spoken or written language because of brain injury or disease.
Arrhythmia (or dysrhythmia)An abnormal heartbeat
Arrhythmogenic right ventricular dysplasia (ARVD)ARVD is a type of cardiomyopathy with no known cause. It appears to be a genetic condition (passed down through a family's genes). ARVD causes ventricular arrhythmias. The most common symptoms are heart palpitations, fainting or loss of consciousness (syncope), and, sometimes, sudden death.
ArteriolesSmall, muscular branches of arteries. When they contract, they increase resistance to blood flow, and blood pressure in the arteries
ArteryA vessel that carries oxygen-rich blood to the body.
ArteritisInflammation of the arteries.
ArteriosclerosisA disease process, commonly called hardening of the arteries, which includes a variety of conditions that cause artery walls to thicken and lose elasticity.
Ascending aortaThe first portion of the aorta, emerging from the heart's left ventricle.
AtherectomyA non-surgical technique for treating diseased arteries with a rotating device that cuts or shaves away obstructing material inside the artery.
AtherosclerosisA disease process that leads to the accumulation of a waxy substance, called plaque, inside blood vessels
AtriaThe two upper or holding chambers of the heart.
Atrial flutterA type of arrhythmia where the upper chambers of the heart (the atria) beat very fast, causing the walls of the lower chambers (the ventricles) to beat inefficiently as well.
Atrial septal defectA hole in the wall of the heart separating the atria or in the wall of the heart separating the ventricles.
Atrial tachycardiaA type of arrhythmia that begins in the heart's upper chambers (the atria) and causes a very fast heart rate of 160 to 200 beats a minute. A resting heart rate is normally 60 to 100 beats a minute
Atrioventricular blockAn interruption or disturbance of the electrical signal between the heart's atria (upper two chambers) and the ventricles
Atrioventricular (AV) nodeA group of cells located between the atria (upper two chambers) and the ventricles (lower two chambers) that regulates the electrical current (heart rhythm) that passes through it to the ventricles.
AtriumEither one of the heart's two upper chambers.
AutoregulationWhen blood flow to an organ stays the same although pressure changes in the artery that delivers blood to that organ may have changed.
BacteriaGerms that can lead to disease
Bacterial endocarditisA bacterial infection of the lining of the heart's chambers (called the endocardium) or the heart's valves.
Balloon catheterA long tube-like device with a small balloon on the end that can be threaded through an artery. Used in angioplasty or valvuloplasty
Balloon valvuloplastyA procedure to repair a heart valve that is not working properly. A balloon-tipped catheter is threaded through an artery and into the heart. The balloon is inflated to open and separate any narrowed or stiffened flaps (called leaflets) of a valve. The catheter and deflated balloon are removed after the procedure.
Beta blockerAn antihypertensive drug that limits the activity of epinephrine, a hormone that increases blood pressure.
BiopsyThe process by which a small sample of tissue is taken for examination.
Blalock-Taussig procedurePalliative shunt between the subclavian and pulmonary arteries used to increase the supply of oxygenated blood in
Blood clotA jelly-like mass of blood tissue formed by clotting factors in the blood. Clots stop the flow of blood from an injury; they can also form inside an artery whose walls are damaged by atherosclerotic build-up and can cause a heart attack or stroke
Blood pressureThe force or pressure exerted by the heart in pumping blood; the pressure of blood in the arteries
"Blue babies"Babies who have a blue tinge to their skin (cyanosis) resulting from insufficient oxygen in the arterial blood. This condition often
BradycardiaAbnormally slow heartbeat
BruitA sound made in the blood vessels that is a result of turbulence, perhaps due to a buildup of plaque or damage to the vessels
Bundle-branch blockA condition in which portions of the heart's conduction system are defective and unable to conduct the electrical signal normally, causing arrhythmias.
BypassSurgery that can improve blood flow to the heart (or other organs and tissues) by providing a new route, or "bypass," around a section of clogged or diseased artery.
Calcium channel blocker (or calcium blockerA drug that lowers blood pressure by regulating calcium-related electrical activity in the heart.
CapillariesMicroscopically small blood vessels between arteries and veins that distribute oxygenated blood to the body's tissues.
CardiacPertaining to the heart
Cardiac arrestThe stopping of the heartbeat, usually because of interference with the electrical signal (often associated with coronary heart
Cardiac catheterizationA procedure that involves inserting a fine, hollow tube (catheter) into an artery, usually in the groin area, and passing the tube into the heart. Often used in conjunction with angiography and other procedures, cardiac catheterization has become a prime tool for visualizing the heart and blood vessels and diagnosing and treating heart disease.
Cardiac enzymesComplex substances capable of speeding up certain biochemical processes in the cardiac muscle. Abnormal levels of these enzymes signal heart attack
Cardiac outputThe amount of blood the heart pumps through the circulatory system in one minute
CardiologyThe study of the heart and its function in health and disease
Cardiopulmonary bypassThe process by which a machine is used to do the work of the heart and lungs so the heart can be stopped during surgery.
Cardiopulmonary resuscitation (CPR)An emergency measure that can maintain a person's breathing and heartbeat. The person who performs CPR actually helps the patient's circulatory system by breathing into the patient's mouth to give them oxygen and by giving chest compressions to circulate the patient's blood.
Cardiovascular (CV)Pertaining to the heart and blood vessels. The circulatory system of the heart and blood vessels is the cardiovascular system.
CardioversionA technique of applying an electrical shock to the chest in order to convert an abnormal heartbeat to a normal rhythm
CardiomyopathyA disease of the heart muscle that leads to generalized deterioration of the muscle and its pumping ability.
Carotid arteryA major artery (right and left) in the neck supplying blood to the brain.
Cerebral embolismA blood clot formed in one part of the body and then carried by the bloodstream to the brain, where it blocks an artery.
Cerebral hemorrhageBleeding within the brain resulting from a ruptured blood vessel, aneurysm, or a head injury.
Cerebral thrombosisFormation of a blood clot in an artery that supplies part of the brain.
CerebrovascularPertaining to the blood vessels of the brain
Cerebrovascular accidentAlso called cerebral vascular accident, apoplexy or stroke. An impeded blood supply to some part of the brain, resulting in injury to brain tissue
Cerebrovascular occlusionThe obstruction or closing of a blood vessel in the brain.
CholesterolAn oily substance that occurs naturally in the body, in animal fats and in dairy products, and that is transported in the blood. Limited quantities are essential to the normal development of cell membranes.
CineangiographyThe technique of taking moving pictures to show the passage of an opaque dye through blood vessels, which allows physicians to diagnose diseases of the heart and blood vessels.
Circulatory systemPertaining to the heart, blood vessels and the circulation of blood.
ClaudicationA tiredness or pain in the arms and legs caused by an inadequate supply of oxygen to the muscles, usually due to narrowed arteries.
Collateral circulationBlood flow through small, nearby vessels in response to blockage of a main blood vessel.
CommissurotomyA procedure used to widen the opening of a heart valve that has been narrowed by scar tissue. First developed to correct rheumatic heart disease.
Computed tomography (CT or CAT scan)An x-ray technique that uses a computer to create cross-sectional images of the body
Conduction systemSpecial muscle fibers that conduct electrical impulses throughout the muscle of the heart.
CongenitalRefers to conditions existing at birth.
Congenital heart defectsMalformation of the heart or of its major blood vessels present at birth.
Congestive heart failureA condition in which the heart cannot pump all the blood returning to it, leading to a back up of blood in vessels and accumulation of fluid in body tissues, including the lungs.
Coronary arteriesTwo arteries arising from the aorta that arch down over the top of the heart and divide into branches. They provide blood to the heart muscle.
Coronary artery bypass (CAB)Surgical rerouting of blood around a diseased vessel that supplies the heart by grafting either a piece of vein from the leg or the artery from under the breastbone.
Coronary artery disease (CAD)A narrowing of the inside diameter of arteries that supply the heart with blood. The condition arises from accumulation of plaque and greatly increases a person's risk of having a heart attack.
Coronary heart diseaseDisease of the heart caused by atherosclerotic narrowing of the coronary arteries likely to produce angina pectoris or heart attack; a general term.
Coronary occlusionAn obstruction of one of the coronary arteries that hinders blood flow to some part of the heart muscle
Coronary thrombosisFormation of a clot in one of the arteries that carry blood to the heart muscle. Also called coronary occlusion.
CryoablationThe removal of tissue using an instrument called a cold probe.
CyanosisBlueness of skin caused by insufficient oxygen in the blood
Cyanotic heart diseaseA birth defect of the heart that causes oxygen-depleted (blue) blood to circulate to the body without first passing through the lungs
Death rate (age-adjustedA death rate that has been standardized for age so different populations can be compared or the same population can be compared over time.
Deep vein thrombosisA blood clot in the deep vein in the calf.
DefibrillatorAn electronic device that helps reestablish normal contraction rhythms in a malfunctioning heart.
Diabetes (diabetes mellitus)A disease in which the body doesn't produce or properly use insulin. Insulin is needed to convert sugar and starch into the energy needed in daily life.
Diastolic blood pressureThe lowest blood pressure measured in the arteries, it occurs when the heart muscle is relaxed between beats.
DigitalisA drug made from the leaves of the foxglove plant. Digitalis is used to treat congestive heart failure (CHF) and heart rhythm problems (arrhythmias). Digitalis can increase blood flow throughout the body and reduce swelling in the hands and ankles.
Dissecting aneurysmA condition in which the layers of an artery separate or are torn, causing blood to flow between the layers. Dissecting aneurysms usually happen in the aorta, which is the large vessel that carries blood from the heart to other parts of the body.
DiureticA drug that lowers blood pressure by stimulating fluid loss; promotes urine production.
Doppler ultrasoundA technology that uses sound waves to assess blood flow within the heart and blood vessels and to identify leaking valves.
DysarthriaThe imperfect articulation of speech resulting from muscular problems caused by damage to the brain or nervous system.
Dyspnea- A shortness of breath.
EchocardiographyA method of studying the heart's structure and function by analyzing sound waves bounced off the heart and recorded by an electronic sensor placed on the chest. A computer processes the information to produce a one-, two- or three-dimensional moving picture that shows how the heart and heart valves are functioning.
EdemaSwelling caused by fluid accumulation in body tissues.
Ejection fractionA measurement of blood that is pumped out of a filled ventricle. The normal rate is 50 percent or more.
Electrocardiogram (ECG or EKG)A test in which several electronic sensors are placed on the body to monitor electrical activity associated with the
Electroencephalogram (EEG)A test that can detect and record the brain's electrical activity. The test is done by pasting metal disks, called electrodes, to the scalp.
Electrophysiological study (EPS)A test that uses cardiac catheterization to study patients who have arrhythmias (abnormal heartbeats). An electrical current stimulates the heart in an effort to provoke an arrhythmia, which is immediately treated with medication. EPS is used primarily to identify the origin of arrhythmias and to test the effectiveness of drugs used to treat abnormal heart rhythms.
EmbolusAlso called embolism; a blood clot that forms in the blood vessel in one part of the body and travels to another part.
EndarterectomySurgical removal of plaque deposits or blood clots in an artery.
EndocardiumThe smooth membrane covering the inside of the heart. The innermost lining of the heart.
EndotheliumThe smooth inner lining of many body structures, including the heart (endocardium) and blood vessels.
EndocarditisA bacterial infection of the heart's inner lining (endothelium).
Enlarged heartA state in which the heart is larger than normal due to heredity, long-term heavy exercise, or diseases and disorders such as obesity, high blood pressure, and coronary artery disease.
EnzymeA complex chemical capable of speeding up specific biochemical processes in the body.
EpicardiumThe thin membrane covering the outside surface of the heart muscle.
EstrogenA female hormone produced by the ovaries that may protect women against heart disease. Estrogen is not produced after menopause.
Estrogen (or hormone) replacement therapy (ERT or HRT)Hormones that some women may take to offset the effects of menopause.
Exercise stress testA fairly common test for diagnosing coronary artery disease, especially in patients who have symptoms of heart disease. The test helps physicians assess blood flow through coronary arteries in response to exercise, usually walking, at varied speeds and for various lengths of time on a treadmill. A stress test may include use of electrocardiography, echocardiography, and injected radioactive substances. Also called exercise test, stress test or treadmill test.
Familial hypercholesterolemiaA genetic predisposition to dangerously high cholesterol levels.
Fatty acids (fats)Substances that occur in several forms in foods; different fatty acids have different effects on lipid profiles.
FibrillationRapid, uncoordinated contractions of individual heart muscle fibers. The heart chamber involved can't contract all at once and pumps blood ineffectively, if at all.
First-degree heart blockWhen an electrical impulse from the heart's upper chambers (the atria) is slowed as it moves through the atria and atrioventricular (AV) node.
FlutterThe rapid, ineffective contractions of any heart chamber. A flutter is considered to be more coordinated than fibrillation.
Fusiform aneurysmA tube-shaped aneurysm that causes the artery to bulge outward. Involves the entire circumference (outside wall) of the artery.
Gated blood pool scanAn x-ray analysis of how blood pools in the heart during rest and exercise. The test makes use of a radioactive substance injected into the blood to tag or label red cells. The test provides an estimate of the heart's overall ability to pump and its ability to compensate for one or more blocked arteries. Also called MUGA, for multi-unit gated analysis.
Genetic testingBlood tests that study a person's genes to find out if he or she is at risk for certain diseases that are passed down through family members.
Heart assist deviceA mechanical device that is surgically implanted to ease the workload of the heart.
Heart attackDeath of, or damage to, part of the heart muscle due to an insufficient blood supply.
Heart blockGeneral term for conditions in which the electrical impulse that activates the heart muscle cells is delayed or interrupted somewhere along its path.
Heart failureA condition in which the heart cannot pump all the blood returning to it, leading to a back up of blood in vessels and accumulation of fluid in body tissues, including the lungs.
Heart-lung machineAn apparatus that oxygenates and pumps blood to the body during open heart surgery.
Heart murmurAn abnormal heart sound caused by turbulent blood flow. The sound may indicate that blood is flowing through a damaged or overworked heart valve, that there may be a hole in one of the heart's walls, or that there is a narrowing in one of the heart's vessels. Some heart murmurs are a harmless type called innocent heart murmurs, which are common in children and usually do not require treatment.
HeredityThe genetic transmission of a particular quality or trait from parent to offspring.
High blood pressureA chronic increase in blood pressure above its normal range.
High density lipoprotein (HDL)A component of cholesterol, HDL helps protect against heart disease by promoting cholesterol breakdown and removal from the blood; hence, its nickname "good cholesterol."
Holter monitorA portable device for recording heartbeats over a period of 24 hours or more.
HormonesChemicals released into the bloodstream that control different functions in the body, including metabolism, growth, sexual development, and responses to stress or illness.
HypertensionHigh blood pressure.
Hypertrophic obstructive cardiomyopathy (HOCM)An overgrown heart muscle that creates a bulge into the ventricle and impedes blood flow.
HypertrophyTissues or organs that have grown in size because of increased workload.
HyperventilationRapid breathing usually caused by anxiety. Persons feel like they can't get enough air, so they breathe heavily and rapidly, which can lead to numb or tingly arms and legs, or fainting.
HypoglycemiaLow levels of glucose in the blood.
HypotensionAbnormally low blood pressure.
HypoxiaLess than normal content of oxygen in the organs and tissues of the body.
IdiopathicNo known cause.
Immunosuppressive medicationsAny drug that suppresses the body's immune system. These medications are used to minimize the chances that the body will reject a newly transplanted organ such as a heart.
Impedance plethysmographyA noninvasive diagnostic test used to evaluate blood flow through the leg.
Incompetent valveAlso called insufficiency; a valve that is not working properly, causing it to leak blood back in the wrong direction.
InfarctThe area of heart tissue permanently damaged by an inadequate supply of oxygen.
Infective endocarditisAn infection of the heart valves and the innermost lining of the heart (the endocardium), caused by bacteria in the bloodstream
Inferior vena cavaThe large vein returning blood from the legs and abdomen to the heart.
Inotropic medicationsAny drug that increases the strength of the heart's contraction.
Intravascular echocardiographyA marriage of echocardiography and cardiac catheterization. A miniature echo device on the tip of a catheter is used to generate images inside the heart and blood vessels.
IschemiaDecreased blood flow to an organ, usually due to constriction or obstruction of an artery.
Ischemic heart disease- Also called coronary artery disease and coronary heart disease, this term is applied to heart ailments caused by narrowing of the coronary arteries, and therefore characterized by a decreased blood supply to the heart.
Ischemic strokeA type of stroke that is caused by blockage in a blood vessel.
Jugular veinsThe veins that carry blood back from the head to the heart.
LesionAn injury or wound. An atherosclerotic lesion is an injury to an artery due to hardening of the arteries.
LipidA fatty substance insoluble in blood.
LipoproteinA lipid surrounded by a protein; the protein makes the lipid soluble in blood.
Low density lipoprotein (LDL)The body's primary cholesterol-carrying molecule. High blood levels of LDL increase a person's risk of heart disease by promoting cholesterol attachment and accumulation in blood vessels; hence, the popular nickname "bad cholesterol."
LumenThe hollow area within a tube, such as a blood vessel.
Magnetic resonance imaging (MRI)A technique that produces images of the heart and other body structures by measuring the response of certain elements (such as hydrogen) in the body to a magnetic field. When stimulated by radio waves, the elements emit distinctive signals in a magnetic field. MRI can produce detailed pictures of the heart and its various structures without the need to inject a dye.
Mitral stenosisA narrowing of the mitral valve, which controls blood flow from the heart's upper left chamber (the left atrium) to its lower left chamber (the left ventricle). May result from an inherited (congenital) problem or from rheumatic fever.
Mitral valveThe structure that controls blood flow between the heart's left atrium (upper chamber) and left ventricle (lower chamber).
Mitral valve prolapseA condition that occurs when the leaflets of the mitral valve between the left atrium (upper chamber) and left ventricle (lower chamber) bulge into the ventricle and permit backflow of blood into the atrium. The condition is often associated with progressive mitral regurgitation.
Mitral valve regurgitationFailure of the mitral valve to close properly, causing blood to flow back into the heart's upper left chamber (the left atrium) instead of moving forward into the lower left chamber (the left ventricle).
Monounsaturated fatsA type of fat found in many foods but predominantly in avocados and canola, olive and peanut oil. Monounsaturated fat tends to lower LDL cholesterol levels, and some studies suggest that it may do so without also lowering HDL cholesterol levels.
MortalityThe total number of deaths from a given disease in a population during an interval of time, usually a year.
MurmurNoises superimposed on normal heart sounds. They are caused by congenital defects or damaged heart valves that do not close properly and allow blood to leak back into the chamber from which it has come.
Myocardial infarctionThe damage or death of an area of the heart muscle (myocardium) resulting from a blocked blood supply to the area. The affected tissue dies, injuring the heart. Symptoms include prolonged, intensive chest pain and a decrease in blood pressure that often causes shock.
Myocardial ischemiaDeficient blood flow to part of the heart muscle.
MyocardiumThe muscular wall of the heart. It contracts to pump blood out of the heart and then relaxes as the heart refills with returning blood.
Myxomatous degenerationA connective tissue disorder that causes the heart valve tissue to weaken and lose elasticity.
NitroglycerinA drug that helps relax and dilate arteries, often used to treat cardiac chest pain (angina).
NecrosisReferring to the death of tissue within a certain area.
Noninvasive proceduresAny diagnostic or treatment procedure in which no instrument enters the body.
ObesityThe condition of being significantly overweight. It is usually applied to a condition of 30 percent or more over ideal body weight. Obesity puts a strain on the heart and can increase the chance of developing high blood pressure and diabetes.
Occluded arteryAn artery in which the blood flow has been impaired by a blockage.
Open heart surgeryAn operation in which the chest and heart are opened surgically while the bloodstream is diverted through a heart-lung (cardiopulmonary perfusion) machine.
PacemakerA surgically implanted electronic device that helps regulate the heartbeat.
PalpitationAn uncomfortable sensation within the chest caused by an irregular heartbeat.
PancreasThe organ behind the stomach that helps control blood sugar levels.
PancreatitisSwelling (inflammation) of the pancreas.
ParalysisLoss of the ability to move muscles and to feel in part of the body or the whole body. Paralysis may be temporary or permanent
Patent ductus arteriosusA congenital defect in which the opening between the aorta and the pulmonary artery does not close after birth.
Percutaneous transluminal coronary angioplasty (PTCA)A nonsurgical technique for treating diseased arteries by temporarily inflating a tiny balloon inside an artery.
PericarditisInflammation of the outer membrane surrounding the heart. Rheumatic fever, tuberculosis, and many other agents are its possible
PericardiocentesisA diagnostic procedure using a needle to withdraw fluid from the sac or membrane surrounding the heart (pericardium).
PericardiumThe outer fibrous sac that surrounds the heart.
PlaqueA deposit of fatty (and other) substances in the inner lining of the artery wall; it is characteristic of atherosclerosis.
PlateletsOne of the three types of cells found in blood; they aid in the clotting of the blood.
Polyunsaturated fatThe major fat constituent in most vegetable oils including corn, safflower, sunflower, and soybean. These oils are liquid at room temperature. Polyunsaturated fat actually tends to lower LDL cholesterol levels but may also reduce HDL cholesterol levels as well.
Positron emission tomography (PET)A test that uses positron emitting substances to assess information about the metabolism of elements that can be used to indicate whether heart muscle is alive and functioning. A ring of radiosensitive detectors positioned around the chest reconstructs a two- or three-dimensional image of the heart.
Premature ventricular contraction (PVC)An early or extra heartbeat that happens when the heart's lower chambers (the ventricles) contract too soon, out of sequence with the normal heartbeat.
PrevalenceThe total number of cases of a given disease that exist in a population at a specific time.
PulmonaryReferring to the lungs and respiratory system.
Pulmonary embolismA condition in which a blood clot that has formed elsewhere in the body travels to the lungs.
Pulmonary valveThe heart valve between the right ventricle and the pulmonary artery. It controls blood flow from the heart into the lungs.
Pulmonary veinThe blood vessel that carries newly oxygenated blood from the lungs back to the left atrium of the heart
Radionuclide imagingA test in which a harmless radioactive substance is injected into the bloodstream to show information about blood flow through the arteries. Damaged or dead heart muscle can often be identified, as can serious narrowing in an artery.
Radionuclide studiesAny of the diagnostic tests in which a small amount of radioactive material is injected into the bloodstream. The material makes it possible for a special camera to take pictures of the heart.
Radionuclide ventriculographyA diagnostic test used to determine the size and shape of the heart's pumping chambers (the ventricles).
RegurgitationBackward flow of blood through a defective heart valve.
RenalPertaining to the kidneys.
RevascularizationA procedure to restore blood flow to the tissues. Coronary artery bypass surgery is an example of a revascularization procedure.
Rheumatic feverA disease, usually occurring in childhood, that may follow a streptococcal infection. Symptoms may include fever, sore or swollen joints, skin rash, involuntary muscle twitching, and development of nodules under the skin. If the infection involves the heart, scars may form on heart valves, and the heart's outer lining may be damaged.
Rheumatic heart diseaseA disease of the heart (mainly affecting the heart's valves) caused by rheumatic fever.
Risk factorAn element or condition involving a certain hazard or danger. When referring to heart and blood vessels, a risk factor is associated with an increased chance of developing cardiovascular disease, including stroke.
RubellaCommonly known as German measles.
Saccular aneurysmA round aneurysm that bulges out from an artery. Involves only part of the circumference (outside wall) of the artery.
Saturated fatType of fat found in foods of animal origin and a few of vegetable origin; they are usually solid at room temperature. Abundant in meat and dairy products, saturated fat tends to increase LDL cholesterol levels, and it may raise the risk of certain types of cancer.
Second-degree heart blockImpulses traveling through the heart's upper chambers (the atria) are delayed in the area between the upper and lower chambers (the AV node) and fail to make the ventricles beat at the right moment.
Septal defectA hole in the wall of the heart separating the atria or in the wall of the heart separating the ventricles.
SeptumThe muscular wall dividing a chamber on the left side of the heart from the chamber on the right.
ShockA condition in which body function is impaired because the volume of fluid circulating through the body is insufficient to maintain normal metabolism. This may be caused by blood loss or by a disturbance in the function of the circulatory system.
ShuntA connector that allows blood to flow between two locations.
Sick sinus syndromeThe failure of the sinus node to regulate the heart's rhythm.
Silent ischemiaEpisodes of cardiac ischemia that are not accompanied by chest pain.
Sinus (SA) nodeThe "natural" pacemaker of the heart. The node is a group of specialized cells in the top of the right atrium which produces the electrical impulses that travel down to eventually reach the ventricular muscle, causing the heart to contract.
SodiumA mineral essential to life found in nearly all plant and animal tissue. Table salt (sodium chloride) is nearly half sodium.
SphygmomanometerAn instrument used to measure blood pressure.
StentA device made of expandable, metal mesh that is placed (by using a balloon catheter) at the site of a narrowing artery. The stent is then expanded and left in place to keep the artery open.
StenosisThe narrowing or constriction of an opening, such as a blood vessel or heart valve.
StethoscopeAn instrument for listening to sounds within the body.
Stokes-Adams diseaseAlso called third-degree heart block; a condition that happens when the impulses that pace your heartbeat do not reach the lower chambers of your heart (the ventricles). To make up for this, the ventricles use their own "backup" pacemaker with its slower rate. This rhythm can cause severe dizziness or fainting. Stokes-Adams disease is very serious and can lead to heart failure or death.
Streptococcal infection ("strep" infection)An infection, usually in the throat, resulting from the presence of streptococcus bacteria.
StreptokinaseA clot-dissolving drug used to treat heart attack patients.
SternumThe breastbone.
StressBodily or mental tension resulting from physical, chemical or emotional factors. Stress can refer to physical exertion as well as mental
StrokeA sudden disruption of blood flow to the brain, either by a clot or a leak in a blood vessel.
Subarachnoid hemorrhageBleeding from a blood vessel on the surface of the brain into the space between the brain and the skull.
Sudden deathDeath that occurs unexpectedly and instantaneously or shortly after the onset of symptoms. The most common underlying reason for patients dying suddenly is cardiovascular disease, in particular coronary heart disease.
Superior vena cavaThe large vein that returns blood from the head and arms to the heart.
SyncopeA temporary, insufficient blood supply to the brain which causes a loss of consciousness. Usually caused by a serious arrhythmia
Systolic blood pressureThe highest blood pressure measured in the arteries. It occurs when the heart contracts with each heartbeat.
TachycardiaAccelerated beating of the heart. Paroxysmal tachycardia is a particular form of rapid heart action, occurring in seizures that may last from a few seconds to several days.
TachypneaRapid breathing.
Thallium-201 stress testAn x-ray study that follows the path of radioactive potassium carried by the blood into heart muscle. Damaged or dead muscle can be defined, as can the extent of narrowing in an artery.
Third-degree heart blockAlso called Stokes-Adams attack; impulses from the heart's upper chambers (the atria) are completely blocked from reaching the heart's lower chambers (the ventricles). To make up for this, the ventricles use their own "backup" pacemaker with its slower rate.
ThrombolysisThe breaking up of a blood clot.
ThrombosisA blood clot that forms inside the blood vessel or cavity of the heart.
Thrombolytic therapyIntravenous or intraarterial drugs used to dissolve blood clots in an artery.
ThrombusThrombus
ThyroidA gland located in the front of the neck, just below the voice box.
Tissue plasminogen activator (TPA)A clot-dissolving drug used to treat heart attack patients.
Trans fatCreated when hydrogen is forced through an ordinary vegetable oil (hydrogenation), converting some polyunsaturates to monounsaturates, and some monounsaturates to saturates. Trans fat, like saturated fat, tends to raise LDL cholesterol levels, and, unlike saturated fat, trans fat also lowers HDL cholesterol levels at the same time.
Transcatheter interventionAny of the non-invasive procedures usually performed in the cardiac catheterization laboratory. Angioplasty is an example of a transcatheter intervention.
Transesophageal echocardiographyA diagnostic test that analyzes sound waves bounced off the heart. The sound waves are sent through a tube-like device inserted in the mouth and passed down the esophagus (food pipe), which ends near the heart. This technique is useful in studying patients whose heart and vessels, for various reasons, are difficult to assess with standard echocardiography.
Transient ischemic attack (TIA)A temporary, stroke-like event that lasts for only a short time and is caused by a temporarily blocked blood vessel.
TransplantationReplacing a defective organ with one from a donor.
Tricuspid valveThe structure that controls blood flow from the heart's right atrium (upper chamber) into the right ventricle (lower chamber).
TriglycerideThe most common fatty substance found in the blood; normally stored as an energy source in fat tissue. High triglyceride levels may thicken the blood and make a person more susceptible to clot formation. High triglyceride levels tend to accompany high cholesterol levels and other risk factors for heart disease such as obesity.
UltrasoundHigh-frequency sound vibrations, not audible to the human ear, used in medical diagnosis.
Valve replacementAn operation to replace a heart valve that is either blocking normal blood flow or causing blood to leak backward into the heart (regurgitation).
An operation to replace a heart valve that is either blocking normal blood flow or causing blood to leak backward into the heart (regurgitation).Reshaping of a heart valve with surgical or catheter techniques.
Varicose veinAny vein that is abnormally dilated.
VascularPertaining to the blood vessels.
VasodilatorsAny medication that dilates (widens) the arteries.
VasopressorsAny medication that elevates blood pressure.
VeinAny one of a series of blood vessels of the vascular system that carries blood from various parts of the body back to the heart; returns oxygen-depleted blood to the heart.
Ventricle (right and left)One of the two lower chambers of the heart.
Ventricular fibrillationA condition in which the ventricles contract in a rapid, unsynchronized fashion. When fibrillation occurs, the ventricles cannot pump blood throughout the body.
Ventricular tachycardiaAn arrhythmia (abnormal heartbeat) in the ventricle characterized by a very fast heartbeat.
VertigoA feeling of dizziness or spinning.
Wolff-Parkinson-White syndromeA condition in which an extra electrical pathway connects the atria (two upper chambers) and the ventricles (two lower chambers). It may cause a rapid heartbeat.
X-rayForm of radiation used to create a picture of internal body structures on film.

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