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Peds Emergency Medications for PALS

AB
Epinephrine classificationcatecholamine
Epinephrine actionsincreases heart rate, peripheral vascular resistance and cardiac output, during CPR increases myocardial and cerebral blood flow
Epinephrine doseIV/IO: 0.01 mg/kg of 1:10,000 solution (equals 0.1 mL/kg of the 1:10,000 solution); repeat every 3-5 min
Amiodarone classificationatrial and ventricular antiarrhythmic
Amiodarone actionsslows AV nodal and ventricular conduction, increases the QT interval and may cause vasodilation
Amiodarone dose for VF/PVTIV/IO; 5 mg/kg bolus
Amiodarone dose for perfusing VT or perfusing SVTIV/IO; 5 mg/kg over 20-60 min
Amiodarone max dose15 mg/kg per 24 hours
Amiodarone precautions (side effects)hypotension, Torsades, half-life is up to 40 days
Lidocaine classificationventricular antiarrhythmic
When should Lidocaine be considered?When amiodarone is unavailable
Lidocaine actionsdecreases ventricular automaticity, conduction and repolarization
Lidocaine dose in VF, PVT, or perfusing VTIV/IO; 1 mg/kg bolus every 5-15 minutes
Lidocaine infusion dose20-50 mcg/kg/min
Licocaide precautions (side effects)hypotension and bradycardia
Procainamide classificationatrial and ventricular antiarrhythmic to consider for perfusing rhythms
Procainamide dose for perfusing recurrent VT or recurrect SVTIV/IO; 15 mg/kg infused over 30-60 min
Procainamide precautions (side effects)hypotension; use it with extreme caution with amiodarone as it can cause AV block
Drug of choice for pediatric bradycardia after oxygen and ventilationEpinephrine
Vagtolytic to consider for bradycardia after oxygen, ventilation, and epinephrineAtropine
Atropine actionsBlocks vagal input therefore increases SA node activity and improves AV conduction
Atropine dose0.02 mg/kg; may double amount for second dose
Atropine max doseschild - 1 mg; adolescent - 2 mg
Atropine precautions (side effects)do not give less than 0.1 mg, or may worsen the bradycardia
Drug of choice for symptomatic SVTAdenosine
Adenosine actionblocks AV node conduction for a few seconds to interrupt AV node re-entry
Adenosine doseFirst: 0.1 mg/kg with max of 6mg; second: 0.2 mg/kg with max of 12 mg
Adenosine precautions (side effects)transient AV block or asystole; has very short half-life
Dobutamine classificationsynthetic catecholamine
Dobutamine actionsincreases force of contraction and heart rate; causes mild peripheral dilation; may be used to treat shock
Dobutamine doseIV/IO infusion of 2-20 mcg/min
Dobutamine precautions (side effects)tachycardia
Dopamine classificationcatecholamine
Dopamine actionsdose dependent; may be used to treat shock
Dopamine low dose effectsincreases force of contraction and cardiac output
Dopamine medium dose effectsincreases peripheral vascular resistance, BP, and cardiac output
Dopamine high dose effectshigher increase in peripheral vascular resistance, BOP, cardiac work and oxygen demand
Glucose actionsincreases blood glucose in hypoglycemia; prevents hypoglycemia when insulin is used to treat hyperkalemia
Glucose doseIV/IO; 0.5-1 g/kg; this equals 2-4 mL/kg of D25 OR 5-10 mL/kg of D10 OR 10-20 mL/kg of D5
Glucose precautions (side effects)max recommended should not exceed D25%; hyperglycemia may worsen neuro outcome
Naloxone classificationopiate antagonist
Naloxone actionsreverses respiratory depression effects of narcotics
Naloxone dose for < 5 years or 20 kgIV/IO; 0.1 mg/kg
Naloxone dose for > 5 years or 20 kgIV/IO; up to 2 mg
Naloxone precautions (side effects)half-life is usually less than that of the narcotic, so repeat dosing is often required
Sodium bicarb classificationpH buffer for prolonged arrest, hyperkalemia, tricyclic overdose
Sodium bicarb actionincreases blood pH helping to correct metabolic acidosis
Sodium bicarb dose1 mEq/kg clow bolus; give only after effective ventilation is established
Sodium bicarb precautions (side effects)causes other drugs to precipitate so flush IV tubing before and after


Martinsburg, WV

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