The antiphospholipid antibody can be both an acquired as well as a rare inherited disorder. The diagnosis and management of this thrombotic and autoimmune disease is a major challenge. The references below highlight many of the clinical and laboratory issue for this clinicopathologic disorder. Study Questions What are the criteria used to establish a dx of APL syndrome ? Why do these antibodies induce thrombosis ? How does Plaquenil inhibit thrombosis ? How should arterial thrombosis be treated ? What is a lupus anticoagulant ? Latest randomized control study:
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