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Defense Against Disease

AB
nonspecific resistanceprotects against all pathogens but not against a specific pathogen
mechanical barriersskin, mucous membranes, tears, saliva, urine flow
chemical actionslysozyme, mucus, acids, pepsin, interferon
phagocytosisengulfing and digestion of pathogens
macrophagesmonocytes that have migrated into tissue to engulf (by phagocytosis) pathogens
inflammationlocalized response to infection or injury; redness, pain, swelling, pain, heat
pusaccumulation of living and dead leukocytes, tissues cells, and bacteria
immunityspecific resistance to a specific pathogen; has a "memory"
antigen-presenting cellmacrophage and helper T cell that starts the immune respons
plasma cellsB cells that produce antibodies
memory B cellsremain after infection to "remember" the immune response so a secondary response to the pathogen is faster
B cellsproduce a clone of plasma cells and memory B cells
killer T cellsbind to antigens of pathogen cell and rupture it's cell membrane, killing the cell
suppressor T cellssop an immune reponse after pathogen has been destroyed
memory T cellsdormant cells that are activated if the same antigen fits their receptors; launches a secondary immune response
immunoglobulinsanother name for antibodies
primary immune responsefirst encounter to fight a pathogen; produces memory cells
secondary immune responsewhen B and T memory cells recognize a pathogen from another immune response; much more rapid and intense
active immunityperson is directly involved in the development of the immunity; longer lasting
passive immunityperson is not directly involved in the immunity
naturally acquired active immunityperson contracts disease, recovers, and makes its own memory cells
artificially acquired active immunityperson receives vaccine or
naturally acquired passive immunityinfants receive antibodies via placenta or mom's milk
artificial aquired passive immunityreceiving injections of antibodies from another person or animal; tetanus antitoxin from horses


AP Biology, Anatomy, and Physiology Instructor
Watertown High School and Lake Area Technical Institute

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