| A | B |
|---|
| Cranio-Sacral outflow | Parasympathetic Nervous System |
| Thoraco-Lumbar outflow | Sympathetic Nervous System |
| Ganglion | Collection of nerve cell bodies outside the CNS |
| Nuclei | Collection of nerve cell bodies within the CNS |
| Pre-ganglionic parasympathetic nerve fibers | cholinergic fibers |
| Pre-ganglionic sympathetic nerve fibers | cholinergic fibers |
| Post-ganglionic parasympathetic nerve fibers | cholinergic fibers |
| Post-ganglionic sympathetic nervefibers | adrenergic fibers (mostly) |
| sweat secretion | stimulated by sympathetic CHOLINERGIC fibers |
| SA node | predominantly controlled by Vagus n.(cholinergic) |
| peripheral vascular smooth muscle | contracted by sympathetic (adrenergic) fibers |
| bronchial smooth muscles | constrict upon parasympathetic (cholinergic) stimulation |
| bronchial smooth muscles | dilate upon sympathetic (adrenergic) stimulation |
| atropine | competitive blocker at mAChR |
| curarine | competitive blocker at nAChR |
| mACh receptors | found at cholinergic synapses of smooth muscles |
| mACh receptors | found at cholinergic synapses of exocrine glands |
| mAChR | stimulation will increase (exocrine) glandular secretions |
| mAChR | blockade will decrease (exocrine) glandular secretions |
| nACh receptors | found at neuro-muscular junction (NMJ) |
| Meuro-muscularJunction (NMJ) | a cholinergic synapse |
| nAChR | found in the end-plate region of skeletal muscles |
| nAChR stimulation | will increase skeletal muscle tone |
| overstimulation of nAChR | can cause 'muscle spasms' |
| nicotine | stimulates AChR at NMJ and in autonomic ganglia |
| muscarine | stimulates mAChR in smooth muscles and exocrine glands |
| alpha-adrenergic receptors | predominate in the peripheral vascular smooth muscle |
| alpha-adrenergic receptor stimulation | will cause vasoconstriction and increase BP |
| beta-adrenergic receptor stimulation | will cause vasodilation in peripheral vasculature |
| beta-adrenergic receptor stimulation | will result in positive ino-tropic effect on myocardium |
| alpha-adrenergic receptor stimulation | in SA node will cause positive chrono-tropic effect on heart |
| beta-adrenergic receptor blockers | will decrease myocardial force of contraction and reduce cardiac output |
| alpha-adrenergic receptor blockers | will prevent sympathetic vasoconstriction and reduce BP |
| beta-adnergic receptor stimulation | will cause broncho-constriction |
| ACh Esterase (AChE) | foundin ALL cholinergic synapses |
| AChE | hydrolyzes the ester bond in acetylcholine |
| AChE inhibition | will increase synaptic transmission at ALL cholinergic synapses |
| AChE inhibitors | will cause salivation, lacrimation, urination, and defecation |
| sphincter muscles of iris | constricted by parasympathetic stimulation |
| radial muscles of iris | contracted by sympathetic stimulation |
