| A | B |
| Marquette and Jolliet | first Europeans to reach Missouri |
| de La Salle | explored all the way to Gulf of Mexico |
| de Bourgmont | first European to explore Missouri River |
| Chouteau | founded St. Louis |
| Columbus | first person who discovered the Americans |
| Jefferson | President who bought the Louisiana Purchase |
| Lewis and Clark | explored the Louisiana Purchase |
| Beckwourth | mountain man |
| Becknell | established the Santa Fe Trail |
| Independence | city where the Oregon Trail began |
| Gateway to West | nickname for state of Missouri |
| archaeologists | scientists who dig up remains and objects |
| Osage Indians | tribe nicknamed "Little Ones" |
| explorer | a person who travels to unfamiliar places |
| Louisiana Purchase | doubled the size of the United States |