| A | B |
| St. Augustine | A port city in northeast Florida. The Oldest city in the U.S., founded by the Spanish. |
| Don Juan de Onate | Conquistador from Mexico who founded Santa Fe, New Mexico |
| mission | a settlement where missionaries lived and worked |
| El Camino Real | A number of routes that connected Spain's colonies in the American Southwest to Mexico |
| Antonio de Otermin | Spanish governor of New Mexico |
| Pope | Pueblo leader who drove the Spanish out of New Mexico for 12 years |
| Diego de Vargas | Commander of the Spanish army that recaptured New Mexico from the Pueblo people |
| Junipero Serra | Missionary who built missions in California |
| coureurs de bois | In New France, a person who trapped furs without permission from the French government |
| voyageur | a trader who transported furs by canoe in New France |
| Jean Baptiste Pointe du Sable | Haitian fur trader who established a trading posts that later became the city of Chicago. |
| portage | a land route from one body of water to another. |
| Robert La Salle | French explorer who claimed the Mississippi River valley for France |
| Jacques Marquette | Priest from France who sailed with Louis Jolliet through the Great Lakes and down the Mississippi |
| Quebec | The first permanent French colony in North America |
| George Washington | 1st President of the U.S. He fought in the French and Indian War and led the Continental Army during the American Revolution |
| French and Indian War | A conflict between Great Britain and France in North America from 1754-1763 |
| Ohio River Valley | The region along the banks of the Ohio River |
| Fort Duquesne | A fort built by the French in 1754 where Pittsburgh stands today |
| Fort Necessity | A temporary fort built 60 miles south of Fort Duquesne in 1754 by troops under George Washington's command |
| Edward Braddock | British general in the French and Indian War who died at the Battle of Fort Duquesne |
| Treaty of Paris 1763 | An agreement signed by Great Britain and France that brought an end to the French and Indian War |
| Pontiac | Ottawa chief who led attacks against the British after losing the French and Indian War |
| Proclamation of 1763 | An official announcement by King George III of Great Britain outlawing colonial settlements west of the Appalachian Mountains |