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Musculoskeletal Disorders

AB
Osteoarthritis pathophysiologydeterioration of cartilage and bone ends of joints
Osteoarthritis etiologyRelated to risk factors (age, obesity, physical activities causing repeated stress, trauma, diseases, congenital
Osteoarthritis S/Sjoint pain/stiffness, increased pain with activity, may have nodes on joints of fingers called Heberden's nodes or Bouchard's nodes
Osteoarthritis DiagnosisXray, CT, MRI - but usually history, symptoms, and clinical findings
Osteoarthritis TreatmentNSAID's, muscle relaxants, Cox 2 inhibitors like celebrex, alternating rest with exercise, splint joints, heat/cold, weight loss, surgery to replace joint
Rheumatoid Arthritis (RA) Pathophysiologyinflammation of synovium (lining of joint), synovium becomes thick, fluid accumulates, joint swells, destructive process begins, destruction causes new tissue growth which is eventually converted to bone tissue causing immobility of joint
RA Etiologygenetics is the best guess - really unknown - the rheumatoid factor triggers an autoimmune response
RA S/Svaries with disease progression - minor as dull aching; as major as tremendous pain and can even affect other systems such as glands, liver, and blood
RA diagnosisblood tests such as RF (rheumatoid factor, RBC's which will be decreased, C4 compliment (decreased), ESR (increased), ANA (positive), CRP (positive)
RA treatmentsalicylates, NSAID's, gold injections, chemotherapy agents like methotrexate, prednisone; also heat/cold, rest/activity alternating, surgery


School of Practical Nursing
James Rumsey Technical Institute
Martinsburg, WV

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