| A | B |
|---|
| drug | chemical that alters functioning of living organisms |
| pharmacology | study of drugs & their actions on living organisms |
| addiction | physical or psychological dependence on a drug |
| pharmacokinetics | study of how drugs are absorbed, distributed, metabolized and excreted in the body |
| incompatability | chemical interaction between two drugs which inhibits drug effectiveness or leads to toxicity |
| unbound drug | portion of drug not attached to a protein, the active drug |
| intramuscular route | route dependant upon muscle mass, blood flow & activity |
| receptor | site where a drug acts |
| desired action | the expected response from a drug |
| agonist | drug which interacts with a receptor and stimulates a response |
| side effect | a predictable reaction to a drug though not the desired action |
| oral route | route dependent upon salivary flow, gastric acidity & peristaltic rate |
| teratogen | a drug that induces birth defects |
| topical route | route dependent upon dermal thickness & blood perfusion |
| tolerance | need for increasingly higher doses to achieve a response |
| cumulative effect | the buildup of a drug in the system prolonging or intensifying the desired effect |
| antagonist | drug that binds to a receptor and inhibits the activity of another drug |
| bioavailability | measure of the extent of a drug absorption |
| biotransformation | metabolization or the breakdown of a drug to an excretable form |
| chemical name | describes the chemical component of a drug |
| drug interaction | alteration in the pharmacologic activity of a given drug caused by the presence of one or more additional drugs |
| duration of action | the length of time the drug elicits a therapeutic response |
| first pass effect | initial metabolism of a drug before the drug reaches the circulation |
| generic name | name recognized internationally |
| trade name | registered trademark name given by manufacturer |
| half life | time required for half of the drug to be eliminated from the body |
| onset of action | time required for a drug tp elicit a therapeutic response |
| peak effect | time required for a drug to reach its maximum effect |
| pharmacokinetics | the study of the influence of the body on the drug |
| therapeutic drug monitoring | process of measuring peak and trough levels to ensure a drugs effectiveness |
| therapeutic index | ratio between toxic and therapeutic levels of a drug |
| toxic | drug becomes a poison to the body |
| liver | primary site for drug metabolization |
| kidneys | primary route for drug excretion |
| absorption | process that drug passes from administration site to body fluids |
| distribution | how drug moves through the body |
| excretion | drug elimination from the body |
| steady state | amount of drug entering body = amount of drug exiting body |
| affinity | an attraction for |
| age | biggest influencing factor on drug action |
