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Toll-like receptors

Match the Toll-like Receptors to their PAMPs; the TLRs to their respective membranes and identify the downstream transcrition products

AB
bacterial triacylated lipopeptidesTLR1
Bacterial peptidoglycan and lipoproteinTLR2
bacterial porinsTLR2
lipotechoic acid, bacterial di- and tri-acylated lipopeptidesTLR2
viral hemagglutininTLR2
Gram-negative LipopolysachharidesTLR4
Fungal mannansTLR4
parasitic phospholipidsTLR4
viral envelope proteinsTLR4
host shock proteinsTLR4
bacterial flagellinTLR5
lipotechoic acid, diacylated lipopeptidesTLR6
TLR 1Plasma membrane
TLR2Plasma membrane
TLR4Plasma membrane
TLR5Plasma membrane
TLR6Plasma membrane
viral double strand RNATLR3
viral single strand RNATLR7/TLR8
viral and bacterial unmethylated CpG DNATLR9
TNFINFLAMMATORY CYTOKINES
IL-1INFLAMMATORY CYTOKINES
IL-12INFLAMMATORY CYTOKINES
IL-8CHEMOKINES
MCP-1CHEMOKINES
RANTESCHEMOKINES
E-SELECTINENDOTHELIAL ADHESION MOLECULES
CD80COSTIMULATORY MOLECULES
CD86COSTIMULATORY MOLECULES
IFN alpha/betaANTI-VIRAL CYTOKINES
TLR3Endosomal Membrane
TLR7Endosomal Membrane
TLR8Endosomal Membrane
TLR9Endosomal Membrane



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