| A | B |
|---|
| bacterial triacylated lipopeptides | TLR1 |
| Bacterial peptidoglycan and lipoprotein | TLR2 |
| bacterial porins | TLR2 |
| lipotechoic acid, bacterial di- and tri-acylated lipopeptides | TLR2 |
| viral hemagglutinin | TLR2 |
| Gram-negative Lipopolysachharides | TLR4 |
| Fungal mannans | TLR4 |
| parasitic phospholipids | TLR4 |
| viral envelope proteins | TLR4 |
| host shock proteins | TLR4 |
| bacterial flagellin | TLR5 |
| lipotechoic acid, diacylated lipopeptides | TLR6 |
| TLR 1 | Plasma membrane |
| TLR2 | Plasma membrane |
| TLR4 | Plasma membrane |
| TLR5 | Plasma membrane |
| TLR6 | Plasma membrane |
| viral double strand RNA | TLR3 |
| viral single strand RNA | TLR7/TLR8 |
| viral and bacterial unmethylated CpG DNA | TLR9 |
| TNF | INFLAMMATORY CYTOKINES |
| IL-1 | INFLAMMATORY CYTOKINES |
| IL-12 | INFLAMMATORY CYTOKINES |
| IL-8 | CHEMOKINES |
| MCP-1 | CHEMOKINES |
| RANTES | CHEMOKINES |
| E-SELECTIN | ENDOTHELIAL ADHESION MOLECULES |
| CD80 | COSTIMULATORY MOLECULES |
| CD86 | COSTIMULATORY MOLECULES |
| IFN alpha/beta | ANTI-VIRAL CYTOKINES |
| TLR3 | Endosomal Membrane |
| TLR7 | Endosomal Membrane |
| TLR8 | Endosomal Membrane |
| TLR9 | Endosomal Membrane |
