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microbugs

AB
Streptolysin-OASO titer; forms pores
SPEstreptococcal pyogenic exotoxin
Erysipelasstrep;dermis + dermal lymphatics
ARFMproteins;Ag/ab complexes activate C'
Streptococcus agalactiaeneonatal menningitis
Viridansnormal flora;endocarditis
Brucellosisbang's disease;undulant fever;Malta fever
f.tularensisrequires cysteine media
Pasteurella-multicodacat or dog bite
Yersiniaprotein capsule
Yersinia-pestisYops
Yersiniaflea bite
Flagellatesgiardia; trichomonas; leishmania
Kinetoplastblepharoplast + parabasal body
Promastigoteleishmaina within insects (slides)
Epimastigotetrypansisomes within insects
Trypomastigotetrypanosomes within mammalian host (slides)
Amastigotesleischmania
Leishman-donovan-body(slide)
Kala-azarrodents/dog bite; greysish pigment;visceral leishmaniasis
Grey pigmentthrombocytopenia due to decreased megakaryocytes
CA-19colon cancer marker
strep-throatS.pyrogenes
S.agalactiasesepsis in newborns
Lancefield-antigencell wall carbs define pyogenic strep
GBSS. pyogenes
GASS.galactiae
pneumoccocicapsule composed of polysaccharide polymers
alpha-hemolyticw/variable antigen specificity
beta-hemolysisstreptolysin O/S
streptolysin-Ooxygenlabile;no hemolysis
SPE-Bpyrogenic exotoxin;enzy.clvg ECM;fibro/vitronectin
SPEstreptococcal pyrogenic exotoxsuperantigen
streptokinaselysis of fibrin clots;plsmngen to plasmin
strep-ECM-productsC5a peptidase; streptokinase
ARFaccute rheumatic fever
ARF-effectsprolonged febrile inflam. of infected tis.
rhematic-heart-diseaserecurnt epsds cause heart valve scars
impetigosuprfcl skin colonization
impetigoS. pyrogenes + trauma=alt M-protein
M-proteinCD46 on keratinocytes
protein-Fattack langerhans cells
formation-of-protein-Ffavored by high O2
FORMATION-OF-M-PROTEINFAVORED BY HIGH CO2
c3breceptors for phagocytes
c3aliberates mastc histamn; ^resp burst
salmonella-tyshummuriumcommonc ause of food poisoning
haemphilus-influenzaesinnusitus;middle ear infect
h-influenzae-capsule-Bmeninggitis;epiglotitis
Legionarie'semergent b/c of aerosol;usually protozoan
e.coli-0157:H7spread via food processing
salmonella-camphylobactespread by food processing
rhinovirusbinds to ICAM-1
Shigelladystentary;enzy dislv vesicle membrn
listeria-monocytogenesmeningitis&sepsis in yng+old
mycobacteriuminhibit acidification of phagosome
toxoplasma-gondiiinhibit acidification of endosome/fusion
siderophoremacrophage containing hemosiderin
Tuberculosisacid-fast bacilli
LeprosyAcid-fast bacilli in macrophages
SyphilisTreponema pallidum
Cat-scratch diseaseGram-negative bacillus
Tuberculosiscaseating tubercle:central amorphous granular debris;loss of all cellular detail
Leprosynon-caseating granulomas
SyphilisGumma:microscopic to grossly visible lesion;enclosing wall of histiocytes
Cat-scratch diseaseRounded or stellate granuloma containing central granular debris and recognizable neutrophils
Syphilisplasma cell infiltrate; central cells are necrotic without loss of cellular outline
Cat-scratch diseasegiant cells uncommon



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