| A | B |
|---|
| LTR | transcription of viral genome |
| integration viral DNA into host genome | LTR |
| LTR | binding site for host trans. fx |
| gag | nucleocapsid core, matrix proteins |
| pol | reverse transcript-,prote-,integr-, ribonucle-ase |
| env | viral coat proteins gp 120 gp41 |
| vif | fights host APOBEC3G enzyme |
| vpr | + viral rep.; infection of macs |
| tat | required for elongation |
| rev | nuclear export spliced viral RNA |
| vpu | viral release, downregulates CD4 |
| nef | downregulates CD4, MHC-I, viral release |
