| A | B |
|---|
| ERYSPELAS | STREP-SPREADING ERYTHEMA |
| BURNS | P.aeruginosa |
| Puerperal | myometrial infection; life threatening |
| SCARLET-FEVER | STRWBRY TNG |
| PLATELETS | TXA2 |
| THROMBOXANE-SYNTHASE | TXA2 |
| PEYER’SPATCHES | M-CELLS |
| HYPERALGESIS | PGE2 |
| PGD2 | MAST CELLS CYCLOOXYGENASE |
| BALT | BRONCHUS ASSOCIATED LYMPHATIC TISSUE |
| LXA4/B4 | 5-HPETE 12-LIPOXYGENASE |
| LIPOTOXIN-A4/B4 | VASODL. MONOCT ADHESION |
| CYCLOOXYGENASE | AA PRSTAGLNDN G2 |
| 5-HPETE | AA 5-LIPOXYGENASE |
| PGI2 | PROSTACYCLIN SYNTHETASE |
| CHEMOTAXIS | 5-HETE LEUKOTRIENE B4 |
| INTENSE-VASOCONSTRICTION-CYS | LTC4 |
| CRP-FIBRINOGEN | ACUTE-PHASE-UP REG.BY IL-6 |
| SAA | ACUTE-PHASE- UP REG. BY TNF |
| ACUTE-PHASE-PROTEINS-BIND | CHROMATIN |
| PERITERIOLAR-SHEATH | SPLEEN |
| PALS | BASOPHILLIC |
| PAF | LATE PHASE RESPONSE |
| C-14α-DEMETHYLASE | FUNGAL P450 |
| C-14α-DEMETHYLASE | LANGOSTEROLERGOSTEROL |
| KETOCONAZOLE | INHIBITS AROMATASE |
| S- aureus | bridge is (Gly)5-D-Ala between lysines. |
| S-aureus | crosslinking catalyzed by a transpeptidase |
| Vancomycin | inh polymerztn or transglycosylase rxn |
| Vancomycin | D-alanyl-D-alanine tm of cw precursor &lipid carrier |
| Vancomycin | blocks linkage to the glycopeptide polymer. |
| β-Lactam antibiotics | cross-bridge w/stem ptd displacing D-ala/ adjacent chain |
| Amphotericin-B | forms pores in fungal cell membrane/binds ergosterol |
| Amphotericin-B | Sm. molecules like K+ esc cause death of the fungal cell |
| Macrolides | bacteriostatic/ rev. bind 50s |
| Erythromycin | macrolide/inhibits the translocation step |
| Tetracyclines | 30S blocks tRNA binds to A site |
| Liposomal-amphotericin-B | treatment of visceral leishmaniasis |
| Fluconazole/itraconazole/voriconazole | ergosterol synthesis |
| Capsofungin | 1-3β glucan synthase/cwall |
| 5-fluorocytosine | nucleic acid synthesis |
| 5-fluorocytosine | permease/cytosine deaminase |
| 5-fluo-specificity | humans lack Cytosine-deaminase humans lack |
| 5-fluo-resistance | fungal cw that lack permease |
| synergism | AmphotericinD+Fluocytosine |
| gag+gaglpol | virus specific poly protein |
| HIV-protease-specificity | dimer vs. monomer |
| RITONOMIR+LOPENAVIR-↑ | profound synergism |
| Acyclovir-specificity | thimadine kinase |
| Gancyclovir | UL-97 phosphokinase |
| Penciclovir | varicella zoster |
| Penciclovir | prodrug=famciclovir |
| dihydropteroate-synthase | Sulfonamides compete w/PABA |
| dihydrofolate-reductase | trimethoprim |
| Terbinafine | langosterol synthesis |
| Enfuvertide | inhibits attachment/fusion gp40 |
| NRTL | TOX:INH. MITC REPLICATION |
| NRTL | MOA COMPETITION CHAIN TERM |
| NNRTI | NON-COMPETITIVE IH HIV RT |
| ACYCLOVIR-ACTIV/SPECIF | THYMIDINE KINASE |
| ACYLOVIR-MOA | DGTP CHAIN TERMINATION |
| ACYCLOVIR-RESIST | TKINASE |
