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Chapter 14: Human Disorders Vocabulary

Review of Chapter 14 vocabulary

AB
genetic disorderabnormal condition a person inherits thru genes or chromosomes
mutationsgenetic disorders are caused by ___, changes in a persons DNA
Cystic Fibrosisabnormally thick mucus in the lungs and intestines, making it hard to breathe; caused by recessive allele
Sickle Cellmis-shapen, or sickled, red blood cells; damage to many tissues; caused by codominant alleles
Down Syndromegenetic disorder due to an extra copy of chromosome #21
sex-linkedoften called Genes on the X chromosome
carrierperson who had one recessive allele for a trait and one dominant allele
pedigreechart or "family tree" that tracks which members of a family have a particular trait
karyotypepicture of homologous chromosomes arranged in pairs
autosomeschromosones that are NOT sex-linked
nondisjunctionerror in meiosis in which homologous chromosomes fail to separate; can lead to chromosomal disorders: down syndrome, klinefelter's syndrome or turner's syndrome
sex chromosomesone of two chromosomes that determine the sex of the individual
PKU (phenylketonuria)a build up of phenylalanine in tissues; mental retardation; caused by recessive allele
Tay-Sachs diseasenervous system breakdown; lipid accumulation in brain cells; early childhood death; caused by recessive allele
Acrondroplasiadwarfism (one form); caused by dominant allele
Huntington diseasemental deterioration; usually appears in middle age; caused by dominant allele
albinismlack of pigment in skin, hair, and eyes; lacks melanin
Hemophiliax-linked recessive; protein that clots blood is missing
Muscular dystrophyweakening & loss of skeletal muscles causing paralysis & death; sex-linked disorder
Colorblindnessx-linked; inability to distinguish colors (red and green)
Turner syndromeXO female; only one X chromosome
Klinefelter's syndromeMales with extra X chromosome; XXY
Trisomyextra human chromosome: 47 chromosome
Monosomyone less chromosome; 45 chromosomes


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