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AP Bio Chapter 3 Vocabulary

Macromolecules and the Origin of Life : Key Terms

AB
AdenineA nitrogen-containing base found in nucleic acids, ATP, NAD, and other compounds.
Alpha helixA prevalent type of secondary protein structure.
Amino acidOrganic compounds containing both NH2 and COOH groups. Proteins are polymers of amino acids.
Beta pleated sheetType of protein secondary structure; results from hydrogen bonding between polypeptide regions running antiparallel to each other.
CarbohydratesOrganic compounds containing carbon, hydrogen, and oxygen in the ratio 1:2:1. Common examples are sugars, starch, and cellulose.
CelluloseA straight-chain polymer of glucose molecules, used by plants as a structural supporting material.
Chemical evolutionThe theory that life originated through the chemical transformation of inanimate substances.
Complementary base pairingThe AT (or AU), TA (or UA), CG, and GC pairing of bases in double-stranded DNA, in transcription, and between tRNA and mRNA.
Condensation reactionA reaction in which two molecules become connected by a covalent bond and a molecule of water is released. (AH + BOH → AB + H2O.)
CytosineA nitrogen-containing base found in DNA and RNA.
DenaturationLoss of activity of an enzyme or nucleic acid molecule as a result of structural changes induced by heat or other means.
DeoxyriboseA five-carbon sugar found in nucleotides and DNA.
DissacharideA carbohydrate made up of two monosaccharides (simple sugars).
Disulfide bridgeThe covalent bond between twosulfur atoms (–S—S–) linking to molecules or remote parts of the same molecule.
DNADeoxyribonucleic acid. The fundamental hereditary material of all living organisms. In eukaryotes, stored primarily in the cell nucleus. A nucleic acid using deoxyribose rather than ribose.
Double helixIn DNA, the natural, right-handed coil configuration of two complementary, antiparallel strands.
Ester linkageA condensation (water-releasing) reaction in which the carboxyl group of a fatty acid reacts with the hydroxyl group of an alcohol. Lipids are formed in this way.
FatA triglyceride that is solid at room temperature.
Fatty acidA molecule with a long hydrocarbon tail and a carboxyl group at the other end. Found in many lipids.
Functional groupA characteristic combination of atoms that contribute specific properties when attached to larger molecules.
GlucoseThe most common monosaccharide; the monomer of the polysaccharides starch, glycogen, and cellulose.
GlycerolA three-carbon alcohol with three hydroxyl groups; a component of phospholipids and triglycerides.
GlycogenAn energy storage polysaccharide found in animals and fungi; a branched-chain polymer of glucose, similar to starch.
Glycosidic linkageBond between carbohydrate (sugar) molecules through an intervening oxygen atom (–O–).
GuanineA nitrogen-containing base found in DNA, RNA, and GTP.
HexoseA sugar containing six carbon atoms.
HydrolysisA chemical reaction that breaks a bond by inserting the components of water: AB + H2O → AH + BOH.
IsomersMolecules consisting of the same numbers and kinds of atoms, but differing in the bonding patterns by which the atoms are held together.
LipidsSubstances in a cell which are easily extracted by organic solvents; fats, oils, waxes, steroids, and other large organic molecules, including those which, with proteins, make up the cell membranes.
MacromoleculeA giant polymeric molecule. The macromolecules are proteins, polysaccharides, and nucleic acids.
MonomerA small molecule, two or more of which can be combined to form oligomers (consisting of a few monomers) or polymers (consisting of many monomers).
MonosaccharideA simple sugar. Oligosaccharides and polysaccharides are made up of monosaccharides.
Nucleic acidA long-chain alternating polymer of deoxyribose or ribose and phosphate groups, with nitrogenous bases—adenine, thymine, uracil, guanine, or cytosine (A, T, U, G, or C)—as side chains. DNA and RNA are nucleic acids.
NucleotideThe basic chemical unit in a nucleic acid. A nucleotide in RNA consists of one of four nitrogenous bases linked to ribose, which in turn is linked to phosphate. In DNA, deoxyribose is present instead of ribose.
OilA triglyceride that is liquid at room temperature.
OligosaccharideA polymer containing a small number of monosaccharides.
PentoseA sugar containing five carbon atoms.
Peptide linkageThe bond between amino acids in a protein. Formed between a carboxyl group and amino group (CO—NH–) with the loss of water molecules.
Phosphodiester linkageThe connection in a nucleic acid strand, formed by linking two nucleotides.
PhospholipidsLipids containing a phosphate group; important constituents of cellular membranes.
PolymerA large molecule made up of similar or identical subunits called monomers.
PolysaccharideA macromolecule composed of many monosaccharides (simple sugars). Common examples are cellulose and starch.
Primary structureThe specific sequence of amino acids in a protein.
ProteinOne of the most fundamental building substances of living organisms. A long-chain polymer of amino acids with twenty different common side chains. Occurs with its polymer chain extended in fibrous proteins, or coiled into a compact macromolecule in enzymes and other globular proteins.
PurineOne of the types of nitrogenous bases. The purines adenine and guanine are found in nucleic acids.
PyrimidineA type of nitrogenous base. The pyrimidines cytosine, thymine, and uracil are found in nucleic acids.
Quaternary structureThe specific three dimensional arrangement of protein subunits.
R groupThe distinguishing group of atoms of a particular amino acid.
RiboseA five-carbon sugar in nucleotides and RNA.
RNARibonucleic acid. An often single stranded nucleic acid whose nucleotides use ribose rather than deoxyribose and in which the base uracil replaces thymine found in DNA. Serves as genome from some viruses.
Saturated fatty acidA fatty acid usually containing from 12 to 18 carbon atoms and no double bonds.
Secondary structureOf a protein, localized regularities of structure, such as the alpha-helix and the beta-pleated sheet.
StarchA polymer of glucose; used by plants to store energy.
Structural isomersMolecules made up of the same kinds and numbers of atoms, in which the atoms are bonded differently.
Teritary structureIn reference to a protein, the relative locations in three-dimensional space of all the atoms in the molecule. The overall shape of a protein.
ThymineA nitrogen-containing base found in DNA.
TriglycerideA simple lipid in which three fatty acids are combined with one molecule of glycerol.
Unsaturated hydrocarbonA compound containing only carbon and hydrogen atoms, with one or more pairs of carbon atoms that are connected by double bonds.
UracilA pyrimidine base found in nucleotides of RNA.
VitaminsOrganic compounds that an organism cannot synthesize, but nevertheless requires in small quantity for normal growth and metabolism.

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