A | B |
Fascicles of eosinophilic spindle cells intersecting at right angles | Smooth muscle |
Short fascicles of spindle cells radiating from a central point (like spokes on a wheel)-storiform | Fibrohistiocytic |
Nuclei arranged in columns-palisading | Schwann cell |
Herringbone | Fibrosarcoma |
Mixture of fascicles of spindle cells and groups of epithelioid cells-biphasic | Synovial sarcoma |
Extraosseous Ewing sarcoma and primitive neuroectodermal tumor | FLI-1-EWS fusion gene |
Liposarcoma-myxoid and round cell type | CHOP/TLS fusion gene |
Synovial sarcoma | SYT-SSX fusion gene |
Rhabdomyosarcoma- alveolar type | PAX3-FKHR fusion gene |
Extraskeletal myxoid chondrosarcoma | CHN-EWS fusion gene |
Desmoplastic small round cell tumor | EWS-WT1 fusion gene |
Clear cell sarcoma | EWS-ATF1 fusion gene |
Dermatofibrosarcoma protuberans | COLA1-PDGFB fusion gene |
Alveolar soft part sarcoma | TFE3-ASPL fusion gene |
Congenital fibrosarcoma | ETV6-NTRK3 fusion gene |
Tumors expressing spindle cell | Fibrous, fibrohistiocytic, smooth muscle, Schwann cell |
Tumors expressing small round cell | Rhabdomyosarcoma, primitive neuroectodermal tumor |
Tumors expressing epithelioid | Smooth muscle, Schwann cell endothelial, epithelioid sarcoma |