| A | B |
|---|
| WBC | 5-10K/mm3 |
| RBC | 3.5-5.0/mm3 |
| platelets | 150-400K, under 50K considered critical value |
| Hemoglobin | de13.5-17.5g/dl, delivers O2 and returns CO2 |
| hematocrit | usually three times the hemoglobin |
| Neutrophils | WBC non specific and on constant survailence in the body- second line of defense in the immune system |
| Lymphocytes | 40 % of the total WBC normally; finish maturing in the lymph nodes, they are antigen specific cells |
| Bands | immature neutrophis, indicate overwhelming infection |
| reticulocytes | immature RBC, usually indicate prolonged loss of RBCs |
| Hemophilia | factor VIII deficiency, giveFactor VIII for bleeding! |
| PT | coumadin effects-extrinsic and common pathway |
| PTT | heparin effects-intrinsic pathway |
| T lymph | usually kill viruses, third line of efense in the immune system |
| B lymph | make antibodies, third line of defense in the immune syster |
| CD4+ | conductor of the immune system, necessary for T and B lymphocytes to work together |
| Pernicious anemia | vitamin B12 deficiency, lack of intrisic factor |
| iron deficiency anemia | H/ H low and MCV low; may be a sign of GI loss of cancer in the adult |
| Iron | take on an empty stomach for best absorption |
| Procrit | gentetically engineered erythropoietin- used to treat certain anemias |
| stem cells | found in the bone marrow, responsible for hematopoiesis |
| G-CSF (Neupogen) | stimualtes immature neutrophils to divide and differentiate |
| dysfunctional stem cells | Blood cell numbers are really high or really low and the cells that are made are non-functional |
| Vitamin C | iron is best utilized in body if taken with vitamin C; :also tens to help immune system |
| Folic Acid | essentail for erythropoiesis |
| Life span is 120 days | RBC |
| Life span is 2-4 hours | neutrophils |
| anemia | RBC destruction (hemolysis), decreased production of RBC or loss of RBCs |
| life span is 10 days | thrombocyte (platelet) |
| aplasitc anemia | a cell lines (myeloid and lymphocytic)are depressed, bone marrow aspiration to dx |
| ALL | boys 4years old! can be cured with BMT |
| CML | Gleeve WORKS! super high non- functioning WBCs- s/s vary |
| AML | 60+ years incidence, fever and infection from neutropenia first s/s |
| CLL | the CA Nick had- 60 years old usually- cancer of the B lymphs- lymphoadenopathy and high lymph counts or maybe no symptoms! |
| multiple myeloma | cancer of the plasma cell- cant make antibodies- very painful disease |
| Sicle Cell Anemia (SCA) | Hgb cant carry 02 or CO2- tissuesstarve- chronically anemic and very painful!! |
| Non Hodgkins lymphoma (NHL) | not such a good survival rate as Hodgkins- BMT for a cure usually, seen in immunodeficiencies or immunosuppressed peoplepu |
| Hodgkins Lymphoma | can be cured if caught early, tumors start in lymph nodes, young kids and people over 50 are typical |
| immunocompetent | all pieces of the immune system are they and are working proplerly |
| immunosuppressed | steroids- all players in the immune system are shut down or suppressed |
| immunodeficient | a part of the immune system is missing for multiple reasons |
