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The Fat-Soluble Vitamins: A, D, E, and K (Part 1)

roles in the body, deficiencies, toxicity, recommendations and in which foods

AB
acnea chronic inflammation of the skin's follicles and oil-producing glands
alpha-tocopherolthe most biologically active vitamin E compound
beta-carotenean orange pigment and vitamin A precursor found in plants
carotenoidspigments commonly found in plants and animals
chlorophyllthe green pigment of plants, which absorbs photon & transfer their energy to other molecules
D,L: D stands for dextro, or right handed & L stands for levo or left-handedrefers to the shape of the molecules, which are mirror images of each other
differentiationdevelopment of specific function different from those of the original
epithelial cellscells on the surface of the skin and mucous membranes
epithelial tissuethe layers of the body that serve as selective barriers between the body's interior and the environment
erythrocytered blood cell
erythrocyte hemolysisthe breaking open of red blood cells; a symptom of vitamin E deficiency
fibrocystic breast diseasea harmless condition in which the breast develop lumps, sometime assoc. with caffeine consumption
hair folliclea group of cells in the skin from which a hair grows
hemolysisbursting of red blood cells
hemophiliaa hereditary disease that has no relation to vitamin K, but is caused by a genetic defect
hemophilia is when the blood is unable to clot becauseit lacks the ability to synthesize certain clotting factors
hemorrhagic diseasea disease characterized by excessive bleeding
hypercalcemiahigh blood calcium that may develop from a variety of disorder, including vitamin D toxicity
intermittent claudicationsevere calf pain caused by inadequate blood supply; it occurs when walking and subsides during rest
international units (IU)a measure of vitamin activity
jaundiceyellowing of the skin, due to spillover of the bile pigments bilirubin from the liver into the general circulation
keratina water-insoluble protein; the normal protein of hair and nails
keratinizationaccumulation of keratin in a tissue; a sign of vitamin a deficiency
keratomalaciasoftening of the cornea seen in severe vitamin A deficiency that leads to irreversible blindness
lysosomessacs of degradative enzymes
mendionea synthetic form of vitamin K
mineralizationthe process in which calcium, phosphorus, and other minerals crystallize on the collagen matrix of a growing bone, hardening the bone
mucusa class of substances secreted by the goblet cells of mucous membranes; a glycoprotein
mucous membranesthe membranes, composed of mucus-secreting cells, that line the surfaces of body tissues
muscular dystrophya hereditary disease in which the muscles gradually weaken; its most debilitating effects arise in the lungs
night blindnessslow recovery of vision after flashes of bright light at night or an inability to see in dim light; an early symptom of vitamin A deficiency
osteoblastscells that build bone
osteoclaststhe cells that destroy bone during growth
osteomalaciaa bone disease characterized by softening of the bones; symptoms include bending of the spine and bowing of the legs
preformed vitamin Adietary vitamin A in its active form
RE (retinol equivalent)the amount of retinol that the body will derive from a food containing preformed retinol or its precursor beta-carotene
remodelingthe dismantling or reformation of a structure, in this case, bone.
retinalthe aldehyde form of vitamin A, active in the eye
retinoic acidthe acid form of vitamin A
retinoidschemically related compounds with biologic activity similar to retinol
retinolthe alcohol form of vitamin A
retinol-binding protein (RBP)the specific protein responsible for transporting retinol
ricketsthe vitamin D deficiency disease in children characterized by inadequate mineralization of bone
sterilefree of microorganisms, such as bacteria
tocopherola general term for several chemically related compounds, most of which have vitamin E activity
urethrathe tube through which urine fromt he bladder passes out of the body
vitamin A activitya term useful for referring to the preformed vitamin A and carotene contents of foods w/o dist between them
vitamin D-refractory ricketsa rare type of rickets, not caused by vitamin D deficiency
xanthophylispigments found in plants; responsible for the color changes seen in autumn leaves
xerophthalmiaprogressive blindness caused by vitamin A deficiency
xerosisdrying of the cornea; a sign of vitamin A deficiency


Nancy

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