| A | B |
| TQ! may be poisonous at a given dose and route of admin. | any chemical |
| agencies that are assd with poison control | AAPCC and TESS |
| TQ? The 3 incidences that account for 30% of poisonings in child <6 | cosmetics, cleaning subst., plants |
| the most important reason for poisonings in children | dosing errors |
| reason for dosing errors | household spoons come in different sizes |
| TQ? #1 place for poisonings to occur. | home |
| poison control center staff | pharmacists, nurses, and director (usu MD) |
| TQ! most imp. question when analyzing a poisoning situation | name and phone number |
| TQ! second most imp. quest. in poisoning situation. | How is the patient doing? breathing? coughing? etc. |
| when route of admin. is oral, concerned with...... | lipid solubility, nonionized form, food, first pass, bezoars |
| make oral poisons more readily absorbable | lipid solubility and non-ionized form |
| reason food is bad with oral poisonings | delay abs.->inc. contact time in stomach -> more absorbed |
| mass in stomach that doesn't disolve easily | bezoar |
| Problem with inhalation poisonings | inc. onset bcs rich blood supply and lg. surface area. |
| problem with dermal poisonings | organs most readily avail. to ALL substances, lipid solubility, wounds |
| route of admin of poison with most rapid onset -> mult. organ failure | IV |
| which is more rapid onset: subQ or IM | subQ |
| the least rapid onset | topical |
| which has the most rapid onset: intradermal or IM | IM |
| least rapid onset: oral or IM | oral |
| if know * and *, can determine if the symptoms are consistant w/ amt. ingested and time since exp. | onset and duration of action |
| clinical manifestation of poisoning that -> immed. medical attention. | CV and respiratory involvement |
| some tx modalities are * when certain S/S are present(ie: coma) | contraindicated |
| helps determine the toxicity of substance to pt. and dosing of antidote | age and wt. |
| may complicate tx and influence recommendation | PMH and prior therapy (home remedies or tx) |
| TQ! chemicals that are metabolized to more toxic substances | acetaminophen and methanol |
| database in Micromedix that lists s/s of durgs, avail at PCC | poisindex |
| what do you treat first with a poisoning? | the patient(airway, CV, CNS) not the poison |