| A | B |
| Marco Polo | wrote a book of his travels in China |
| Christopher Columbus | sailed for Spain to discover a westward route to China |
| Christopher Columbus | landed in the Caribbean and took back samples from the islands |
| Cortez | lead an expedition into Mexico and conquered the Aztecs |
| Pizarro | lead a force into South America and conquered the Incas |
| Francisco de Coronado | search the Southwest for Cibola |
| Ponce de Leon | searched in Florida for the "Fountain of Youth" |
| Pedro Menedex de Aviles | founded Ft. Augustine in Florida |
| Juan de Ornate | silver miner in Mexico |
| Jacques Cartier | claimed Canada for France |
| Samuel de Champlain | established Quebec |
| Robert de la Salle | claimed land west of the Mississippi for France |
| Robert de la Salle | explored the Mississippi down to the Gulf Coast |
| Father Marquette | priest who explored the upper Mississippi |
| Louis Joliet | map maker who explored the upper Mississippi |
| John Cabot | claimed Newfoundland and land along the Atlantic for England |
| John Smith | his leadership kept Jamestown alive |
| Chief Powhatan | powerful Indian leader in Virginia |
| Pocahontas | daughter of Powhatan, helped the settlers of Jamestown survive |
| John Rolf | established tobacco as a cash crop in Virginia |
| John Rolf | married Pocahontas |
| Henry Hudson | explored the northern coastline for the Netherlands |
| Henry Hudson | found the Hudson River |
| Peter Minuit | bought Manhattan Island from the native American tribe |
| Peter Stuyvesant, aka (Old Silvernails) | first governor of New Amsterdam, colony on Manhattan Island |
| James, Duke of York | captured New Amsterdam and renamed it New York |
| San Salvador | name given by Columbus to the island he found |
| Columbian exchange | transfer of people, plants, animals, and diseases back and forth across the Atlantic Ocean |
| Northwest Passage | the waterway that would go from the Atlantic to the Pacific |
| Roanoke | colony whose fate was unknown |
| Dutch West India Company | Dutch merchants organized this to trade and establish colonies in the New World |
| Fort Orange | Dutch Fort on upper Hudson river |
| conquistadors | professional Spanish soldiers |
| presidios | Spanish forts |
| coureurs de bois | French trappers or "wood rangers" |
| Taino | tribe encountered by Columbus |
| Aztecs | nation in Mexico |
| Inca | nation in Peru |
| Iroquois | hated the French and Huron |
| Huron | tribes befriended by French |