| A | B |
| substrate | a reactant in an enzyme catalyzed reaction |
| active site | the region of enzyme that interacts with the substrate |
| cofactors | nonprotein compounds required in large molar excess over the enzyme for activity |
| prosthetic | non protein components tightly bound with the enzyme protein |
| km | the michealis menten constant |
| catalyst | material that accelerates the velocity of a reaction |
| hydrolase | catalyze the cleavage of certaion functional groups by water |
| leaving | group displaced by nucleophile |
| transition | unstable high energy state between substrate and product |
| oxidation | loss of electrons by removal of H or addition of O |
| competitive | inhibitors bind at the substrate binding site |
| irreversible | inhibitors that form covalent bonds with the enzyme that are not easily broken |