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Enzymes and Kinetics

AB
substratea reactant in an enzyme catalyzed reaction
active sitethe region of enzyme that interacts with the substrate
cofactorsnonprotein compounds required in large molar excess over the enzyme for activity
prostheticnon protein components tightly bound with the enzyme protein
kmthe michealis menten constant
catalystmaterial that accelerates the velocity of a reaction
hydrolasecatalyze the cleavage of certaion functional groups by water
leavinggroup displaced by nucleophile
transitionunstable high energy state between substrate and product
oxidationloss of electrons by removal of H or addition of O
competitiveinhibitors bind at the substrate binding site
irreversibleinhibitors that form covalent bonds with the enzyme that are not easily broken


Lauren West

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