| A | B |
| Aztec leader when Europeans came to Mexico | Motecuhzoma |
| leader of the Spanish conquistadors who conquered the Aztecs | Hernando Cortez |
| Spanish conquistador who ordered his soldiers to kill the Inca emperor | Francisco Pizarro |
| leader of the Incas killed by the Spanish | Atahuallpa |
| Spanish explorer who looked for the fountain of youth and named present day Florida | Juan Ponce de Leon |
| Spanish explorer who heard stories about the Seven Cities of Gold and went to find them | Francisco Vasquez de Coronado |
| explorer who claimed all of what is the southeastern United States for Spain | Hernando de Soto |
| people who came to the Americas to convert native peoples to Christianity | missionaries |
| people brought to the Americas against their will and forced to work for the colonists | Africans |
| explorer who looked for the Northwest Passage | Jacques Cartier |
| explorer who founded Quebec and Montreal | Samuel de Champlain |
| European who founded a colony at Roanoke that soon disappeared | Sir Walter Raleigh |
| peoples who died from hunger, overwork and diseases after being enslaved by the Spanish | Native Americans |
| Indian who taught the Pilgrims how to fish and plant crops that would do well | Tsuantum |
| conquistador | any of the Spanish conquerors in the Americas in the 1500s |
| civil war | a war between people of the same country |
| grant | a gift of money to be used for a special purpose |
| mainland | the main part of a continent, rather than an island near the continent |
| rumor | a story that hasbeen told but not proved |
| claim | to declare that you or your country owns something |
| desertion | running away from duties, such as military duties |
| colony | a settlement ruled by another country |
| colonist | a person who lives in a colony |
| plantation | a large farm |
| Northwest Passage | a water route that explorers wanted to find so that traders could go through North America to Asia |
| trade network | a system in which trade takes place between certain groups of people |
| agent | a person who does business for other people |
| armada | a fleet of warships |
| profit | in a business, money that is left over after everything has been paid for |
| pilgrim | a person who makes a journey for a religious reason |
| compact | an agreement |
| Mayflower Compact | an agreement by those on the Mayflower to make and obey rules for their colony. This was the first self-rule by American colonists |
| interpreter | one who translates from one language to another |