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DNA

Review of vocabulary from Chapter 6 of Essential Cell Biology by Alberts, et al. (Garland)

AB
antiparallelwhen strands of a biological molecule lie side by side, but with opposite polarity
base pairhydrogen bonded purine and pyrimidine
complementarywhen one thing is present the other is also
complementary base-pairingA bonds to T; G bonds C
DNApolymer of deoxyribonucleotides
DNA polymeraseDNA manufacturing enzyme
DNA repaircorrecting damage to DNA
DNA replicationmaking DNA using DNA as a template
DNA ligaseenzyme that seals nicks in phosphodiester backbone of DNA
double helixspiraling structure formed between complementary, antiparallel strands of DNA
geneexpression unit coding for an RNA
genomeall of the chromosomal DNA in an organism
lagging strandDNA strand being manufactured discontinously
leading strandDNA strand being manufactured continuously
mutationchange in base identity at a specific site in DNA
proofreadingability to find and correct errors
replication forkstructure formed as helix is unwound during DNA synthesis
origin of replicationstart site for DNA synthesis
RNApolymer of ribonucleotides
templateinformation that provides information to make copies
exonucleaseenzyme that cuts nucleic acids from a free end of the molecule
endonucleaseenzymes that cuts nucleic acids in the middle of the molecule
glycolyaseenzyme that creates AP sites
apurinic site/apyrimidic site (AP)place in DNA where the nitrogenous base is removed from a nucleotide
thymine dimerUV light-induced
depurinationDNA damage cause by A and G ring removal
mismatch repaircorrecting incorporation of uncomplementary bases
single strand binding proteinprotein that prevents DNA strands from reannealing
primaseenzyme that makes RNA primers for DNA synthesis
helicaseenzyme that melts hydrogen bonds between base pairs
gyraseenzyme that relieves strain in DNA by unwinding helix
swivelaseprovides same function to replication as gyrase or topoisomerase
Okazaki fragmentsmall piece of DNA from the lagging strand


Professor of Biology
Park University
Parkville, MO

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