| A | B |
|---|
| cidal | killsq |
| static | inhibits growth |
| concers | resistance, residues |
| prevention | educate, label, strong advocates |
| mechanisms of action | 1. interfere with cell walls 2. inhibit protein synthesis 3. interfere with bacerial enzyme synthesis 4. inhibit DNA synthesis |
| Penicllin | -cillin, -cidial. inhibit cell wall synthesis. doesn cross special barriers. adminster on emypt stomch except amoxicillin. procaine causes death in exotics |
| Cephalosporins | ceph or cef. -cidal, classed by generations more resistant to beta-lactamase, don radily cross BBB. can be nephrotoxic |
| Aminoglycoside | micin,mycin, amikacin,-cidal/ inhibit protein synthesis. NO ORAL FORMS, EXCEPT NEOMYACIN. poor BBB, good bronchi HIGHLY NEPHROTOXIC&OTOTOXIC synergistic-cephalosproins |
| Quinolones | -floxacin, interefere with DNA synthesis. renal and hepatic elimination. cartildage damage in young(bubbles) cats no more than 5mg/kg |
| Tetracycline | -cycline, -static. can cause death in horses, avoid in young- stains teeth, expired can cause fanconi's syndrome |
| Sulfanomides | much resistance, DOC for coccidia and toxoplasmosis, crosses barriers well. |
| Sulfasalazine | avoid in cats, GI inflammatory |
| MOA | inactive enzyme needed for bacterum to produce folic acid |
| Lincosamides | -mycin, static or cidal good for pyodermas, dental, osteomyeltis, admimster 2 hours prior to kaolin drugs |
| Macrolids | bacterostatic inhibiy protein synthesis, similar spectrum to penicillin, effective against protozoa and anaerobes. |
| Tilmicosin | CAREFUL! do not use multi dose syringes, prevent eye contact. will KILL you |
| Chloramphenicol | WEAR GLOVES, will kill you. fatal aplastic anemia, penetrates barriers well. if high concentration low dosage. banned for food producing animals |
| Florfenicol | used in cattle for respiratoru diesease. IM 48 hours apart avoid in breeding animals |
| Rifampin | used to treat corynebacterium equi, turns urine, sweat red/orange |
| Bacitracin | neosporin |
| antifungals | superficial-ringworm. deep- histoplasmosis |
| Amphotericin | rapid onset of action -static, nephrotoxic! |
| Griseofulvin | fungistatic to treat trichophyton and microsporums, dog, cats and horses |
