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Pharm 42 - anithyperlipidemic drugs

AB
lipidsgroup of fats in blood
2 lipids in bloodcholesterol triglycerides
LDL - Low density lipoproteinsbad cholesterol - excess of this dump n 2 arteries
HDL - High density lipoproteinsGood cholesterol - takes excess to liver & out of body
types of drugs to treat 4bile acid reductase, fibric acid, HMG-CoA, Niacin
how bile acid reductase worksprevents recirculation of bile acids
major side effect of bile acid reductaseconstipation
Niacinvitamin - works like bile acid dequestrants
side effects of niacinflush, rash, mild h/a
HMG CoA Reductase how workincrease removal of LDL
HMG CoA end instatin
statins take atnight
serious statin side effectrhabdomyolsis - muscle wasting
more HMG CoA -statin adverseliver, h/a GI PROBLEMS
Cholesterol normal levels total150-200
HDL levels45-60
LDL levelsless than 100
triglyceridesless than 150



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