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Pharm - Last Test

AB
1st antiboticsulfonomides
bacteriostatic inhibitsthe activity of folic acid
sulfonomides adversecrystalluria, somatis, urine orange-yellow
how to take sulfonomidesempty tummy, lots of water
Stevens Johnson syndromred blisters or wheal often starting on mouth
sulfonomides make youphotosenstitivity
silvadine creamfor burns, may sting or burn after application
penicillins have ___ in the namecillins
4 groups of penicillin1 natural, 3 natural w/added synethetic
how to take penicillinempty tummy w/full glass of h2o
penicillin V is ok to take withfood
penicillin adverseglossitis, stomatitis, n v d
older adults and penicillinmore likely 2 develop superinfection, have taken penicillin 4 years
pseudomembranous colitis is asuperinfection
pseudomembranous colitis is an overgrowthof clostridium difficle - c-diff
cephalosporins found inspors from sea water - acts like penicillin
if allergice to penicillin, probably allergic tocephalosporins
cephalosporins if taken with boozewill make you throw up
iv cephalosporins need tocheck iv site several times a day
why take cephalosporinsbecause bacteria is resistant to penicillin
cephalosporins adverse ismalaise, nephrotoxicity
how to get TBdroplet - when they cough or sneeze
extrapulmonary - tboutside lungs
usually treat with combo of ___ drugs tb3
antitubercular is the ___ treatmentprimary - provide foundation of treatment
secondary is less effective and more ___toxic - used to treat extrapulmonary
mode of action for TBslows multiplication rate of bacteria
initial drugs (3) tbisoniazid (INH), pyrazinamide, rifampin
isoniazid toxic levels cause (2)peripheral neuropathy, hepatitis
how to take isoniazid drugsempty tummy - 1 hr before, 2 hrs after meals
pyrazinamide causeshepatotoxicity
rifampin causesreddish-orange body fluids, vertigo
teachings tbno booze, no asa, no otc drugs
what they use to treat neuropathyvitamin B6
body fluids of reddish-orange is different thanjaundice
gerontologic alert tbmore susceptible to fatal hepatitis especially w/booze
DOTSdirectly observed therapy - watch pt take drugs
aerobic bacteria needs ___ to flurishoxygen
detection of TBMantoux, PPD, positive chest x-ray
antiviral work bykeep viral cells from replicating
women should ___ get pregnantnot
antieffective isa big umbrella to cover many ways to treat
antiviral - mode of actioninhibit ability to replicate
2 classes to treat viral infectantiviral aniretroviral
generic viral drug have ___ in their namevir
immunocompromised patientscancer, leukemia, transplant, AIDS
zovirax (Acyclovir)Herpes I and II
Amantadineflu type A
Relenza or Tamifluflu type A or B
RibavirinRSV - can make RSV worse
valtrexshingles
retrovirAIDS
gancielovirherpes and CMV
CMVvirus of herpes - can leave u blind
HSVherepes simplex I and II
HIVdestroys immune system causing opportunstic infect
HIV - crivivancan cause kidney stones
AIDS drugs can causenumbness or tingling
antiretroviral drugs can causeredistribution of body fat, fat in center of body
overall antiviral adverse reactionshypotension, visual, prolong penile erection, mental status
diflucanvaginal and mouth candidiasis, memingitis
mycostatinnonesophageal gi membrane candidiasis
mode of action: antifungialable to destroy fungi or retard growth
Antiparasitic - Flagyltreat intestinal amebiasis, trichomoniasis
Antiparasitic - Flagyl side effectsperipheral neuropathy
flagyl biggest side effectdisulfriam like when drink alcohol
fluoroquinolonescipro, floxin, levaquin
floroquinolones treatUTI, lower respiratory, bone/joint infect
aminoglycosides drug examplegentamicin
aminoglycosides treatcolitis, and reduce normal flora for bowel surgery
vancomycinantibotic used to treat superinfections
vancomycin also treatspseudomembranous colitis
vancomycin is ___ used during pregnancynot - or lactation
IV dose vancomycin is given over60 minutes - too soon, pt will drop BP
redman syndrom is (vancomycin)sudden drop BP, redness on neck back
vancomycin may cause you to have ___ urinepink
monitor vancomycin fortinnitus, I&O



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