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Final Med Surge - Infectious Diseases

AB
HIV stands forhuman immunodeficiency virus
HIV1mutates easily & frequently & has multiple strains
HIV2less transmittable - interval between initial infection and onset
HIV1 is more common inUSA
HIV early symptomsflu like, cancer atypical with history
treated w/ antiretroviral drugs toboost immune response
Kaposi sarcomacancer specific to HIV/AIDS
pneumocystic pneumoniaillness can be fatal
opportunistic infectionspneumocystis, candidiasis,
cytomegaloviruseye problems, can lead to blindness
crytosporiosisdiarrhae associated with HIV/AIDS
AIDS dementiadegeneration of brain
4 ways HIV is transmittedblood, semen, vaginal secretions, breast milk
HIV not found inurine, stool, vomit, sweat
Acquited immunodeficiency syndrome isend stage of HIV infection
acute retroviral syndromeflu like symptoms
ELISA, Western Blotinitial screening tests
drug cocktailHAART
treat when Tcount is less than350
distal sensory polyneuropathy feels likeburning, numb
WBC akaleukocytes
WBC produced inbone marrow
stem cellsinitally all blood cells are nospecific
lymphocyteseither T-cell or B-cell
T-cellsmade in marrow, to thymus
T-cell either becomeregulator T-cells or Effector T-cells
Regulator T-cells made ofhelper and suppressor cells
Effector T cellskiller cells aka cytotoxic
Helper T cells purposehelp fight infection
antibodieschemical substances that destory foreign agents
B-cell lymphocytesmature in bm and migrate to spleen
plasma cells produceantibodies
formation of antibodies calledhumoral response
memory cellsconvert to plasma - accumulate in lymph and produce swelling
neutrophils and monocytes arephagocytes
neutrophils akamicrophages - because they are small
lymphoid tissuethymusgland, tonsils, adenoids, slpeen
tonsils and adenoids jobfilter bacteria from tissue fluid
spleen's jobboth hematopoietic and immune function
lymph nodessimilar to capillaries that drain tissue fliud
B-Cells are eitherplasma or memory
phagocytes aka (3)neutrophils, monocytes, microphages
natural killer cellslymphocyte like - move around body looking for virus to kill
immunoglobolins akaantibodies
interferonschemicals that primarily protect cells from viral
anergyinability to mount an immune response
infectious agens akamicroorganisms or germs
emerging microsnew micros - west nile
reemerging microsreappearance of micros - TB whooping
types of infectious agentsbacteria, viruses, fungi, rickettsiae, protozans
communicable or contagiousinfections that can be transmitted person to person
fungiyeast or mold
rickettsiaefleas, ticks, lice, mits
helminthsworms
virulencepower to produce disease
infectious cycleagent, reservoir, exit, transportation, entrance, host
defense mechanisms 2mechanical, chemical
means of transportationcontact, droplet, airborne, vehicle, vector
types of infectionlocalized, generalized, opportunstic
types of infection 2community, nosocomial, acute, chronic, 2ndary
normal WBC4.5 - 11 (thousand)
sepsis is systemticT 100.4 higher, P 90, R20, WBC 12,000
fever is the body's attempto destroy pathogen w/heat
diagnostic testsWBC, culture, sensitivity, skin test
course of infectionincubation, prodromal, acute, convalescent



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