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Anticoagulants

AB
anticoagulantdrug that interferes with clotting
Papaverineantispasmodic used with Heparin
Protamine Sulfateantagonist for Heparin
Protamine sulfate aloneby itself is anticoagulant
concentrations for Heparin10u, 100u, 5,000u, 10,000 and 20,0000u/ml
Enoxaparin (Lovenox)Short acting anticoagulant use as prophylaxis
Oral anticoagulantused for long term management of thrombus formation
warfarin (Coumadin) actioninhibits Vitamin K in liver
Vitamin Kantagonist for Warfarin (Coumadin)
PT - Prothrombin timeused to monitor Warfarin
PTT - Partial thromboplastin timeUsed to monitor Heparin
Side effects of anticoagulantsbruising, epistaxis, hematuria, bleeding
anticoagulant medical useprevent enlargement of clots
prophylactic use of anticoagulantprevent thrombus from stasis
surgical procedure using Heparinperipheral vascular surgery
Irrigation anticoagulation mixture5,000u in 250ml of saline
Peripheral vascular use of Heparin Irrigationused in lumens of blood vessels / shunts
Embolectomyremoval of clot from artery
extracorporeal circulationheart lung bypass
time of action of HeparinIV is immediately
INR - International Normalized RatioComparison of control to Patient PT
1 week preoptime before surgery to discontinue Warfarin
Antithromboticdrug that inhibitis platelet aggregation
Aspirinantithrombotic drug
TIA- Transient Ischemic Attackmini stroke
MI - myocardial infarctionheart attack
Acute conditions and AspirinChest pain or stroke
ASAAspirin
8 to 10 daystime to reverse effect of Aspirin
NASAIDnon steroidal antiinflammatory drug
Thrombolyticdrugs used to dissolve thrombus
thrombolytic drugsTPA, Streptokinaise, Urokinaise
Animocaproic Acid (Amicar)reverses action of thrombolytics
thrombolytic drug concernbleeding from other sites
thrombolytic drug actionActivates plamin to digest fibrin


Instructor / Certified Surgical Technologist
Renton Technical College
Renton, WA

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