| A | B |
| Louisiana Purchase | $15 million purchase of midwestern North America that doubled the size of the U.S. |
| Meriwether Lewis | army scientist who led expedition to explore the Lousiana Purchase |
| William Clark | army map maker who co-led the expedition to explore the Lousiana Purchase |
| Lewis and Clark Expedition | Jefferson's expedition to explore the Louisiana Purchase |
| Sacagawea | Shoshone guide who helped Lewis and Clark |
| Zebulon Pike | led an expedition to find the source of the Red River |
| Napoleon | French leader who sold Louisiana to the U.S. |
| Missouri River | Lewis and Clark's expedition used this to explore the midwest |