| A | B |
| Treaty of Tordesillas | moved the Line of Demarcation |
| missionary | people sent to convert the native people to Christianity |
| mercantilism | an economic system |
| Amerigo Vespucci | Italian sailor who set out in search of a sea route to Asia |
| conquistador | soldiers or conquerors from Spain |
| Hernando Cortes | a conquistador who defeated the Aztecs |
| Montezuma | Aztec emperor |
| Francisco Pizarro | a conquistador who defeated the Incans |
| Henry Hudson | Englishman, sailed for the Dutch looking for a route to China |
| John Cabot | Italian sailor, sailed for English, landed in Canada |
| Giovanni da Verrazzano | Italian explorer, sailed for France in search of the Northwest Passage |
| Jacques Cartier | sailed for France in search of the Northwest Passage |
| Spanish Armada | fleeet of 130 ships sent to conquer England |
| Samuel de Champlain | Frenchman who explored the St. Lawrence River |
| New France | colony founded by Samuel de Champlain |
| slavery | holding a person in bondage for the purpose of labot |
| African Diaspora | removing people from Africa |
| Middle Passage | the voyage from Africa to America |
| Slave Codes | laws that regulated the treatment of slaves |
| Racism | belief that some people are inferior because of their race |
| viceroyalty | provinces in Spain's American empire |
| encomienda | grant of Native American labor |
| hacienda | large estate |
| mission | Spanish settlements built by the Catholic Church |
| Pope | Native American who led a rebellion against the Spanish |
| plantation | large farm that rasied cash crops |
| Bartolome de Las Casas | fought for better treatment of Native Americans |
| Columbian Exchange | movement of living things between hemispheres |