| A | B |
| Columbian Exchange | The movement of people, plants, and germs across the Atlantic Ocean. |
| missionary | A person who teaches his or her religion to people of different beliefs. |
| colony | a settlement far away from the country that rules it |
| Bartolome de la Casas | a Catholic priest who ran an encomienda |
| Francisco Coronado | a young conquistado who lead a group to search for cities |
| conquistador | a Spanish conqueror |
| Nunez Cabeza de Vacca | the first Spaniard to explore Texas |
| Francisco Pizarro | led 180 soldiers against an Indian empire |
| Vasco Nunez de Balboa | he traveled across Central America to become the first European to see the Pacific Ocean |
| Hernando De Soto | explored the American Southeast and was the first European to see the Mississippi |
| Juan Ponce de Leon | stories of Fountain of youth led him to explore Florida |
| encomienda | a very large piece of land in New Spain given by the Spanish government to certain Spanish colonists |