| A | B |
| Stephen A. Douglas | Lincoln's opponent in the 1856 Illinois Senate Race, advocate of popular sovereignty, Author of the Kansas-Nebraska Act. |
| Millard Fillmore | The 13th President, believed that the Compromise of 1850 permanently settled the issue of slavery. |
| David Wilmot | Pennsylvania Congressman who attempted to ban slavery in the territory acquired in the Mexican American War. |
| Henry Clay | Known as the "Great Compromiser", he was the author of the Missouri Compromise and the Compromise of 1850. |
| Harriet Tubman | An escaped slave and one of the most famous Conductors on the Underground Railroad. |
| Harriet Beacher Stowe | Author of Uncle Tom's Cabin |
| John Brown | Anti-slavery activist, took part in "Bleeding Kansas", responsible for the massacre at Potawatomie Creek, led a raid against the federal arsenal at Harper's Ferry, Va in an attempt to launch a slave revolt. |
| Charles Sumner | A Massachusetts Senator and fierce opponent of slavery. He was beaten on the Senate floor after a speech on the "Crimes Against Kansas", was one of the Radical Republicans who led Congressional Reconstruction. |
| Horace Greeley | Founder of the Republican Party. |
| Dred Scott | A slave that sued for freedom in the federal courts on the grounds that living with his master in Illinois (a free state) made him free. |
| Roger Taney | Chief Justice of the Supreme Court and author of the decision in the Dred Scott case. |
| Abraham Lincoln | 16th President of the US, led the country through the Civil War and was assassinated. |
| Jefferson Davis | President of the CSA (Confederate States of America). |
| Stonewall Jackson | General in the Confederate army, killed at Chancellorsville, key aid to Lee |
| George McClellan | Unsuccessful commander of the Union army who is eventually replaced. |
| Ulysses S. Grant | Successful Union General who wins the Battle of Vicksburg, is eventually given command of the entire Union army and is elected President. |
| Robert E. Lee | Commander of the Confederate Army, one of the best generals in American History. |
| Clara Barton | A nurse a several key battles during the war and the founder of the American Red Cross. |
| William T. Sherman | Union general who introduces the concept of total war (war of attrition) and is best known for the "Burning of Atlanta" |
| John Wilkes Booth | Assassinated President Lincoln |
| Andrew Johnson | Lincoln's vice president who was almost impeached. |
| Thaddeus Stevens | A leader of the Radical Republicans and Congressional Reconstruction. |
| Hiram Revels | First African American elected to the Senate. |
| Rutherford B. Hayes | Makes a deal with the Southern states to ensure his election as President, ends reconstruction. |
| Samuel Tilden | Despite winning the popular vote, this man did not become President because of the Compromise of 1877 and its impact on the electoral votes. |