A | B |
Definition of artifact | Deposits artifactually produced by chemicals |
Define Endogenous | Produced by tissue within tissues, serve a physiological function |
Define Exogenous | Gain access into the body accidently, serve no physiological function |
Characteristics of Lipofuchsin | Increase with age, Iron negative gives brown flourescent with UV light, resistant to alcohols and paraffin processing |
Characteristics of Ceroid | Brown acid fast pigment, insoluble in alcohols, negative prussian blue reaction |
Pheochromocytomas are | chromaffin cell tumors of the adrenal gland |
The Grimeluis staining method demonstrates | carcinoid tumors and alpha cells of the pancreas |
Anthrocotic pigment is | black carbon commonly in lymph nodes and lungs |
Oxalosis is | autosomal recessive disease, oxalate deposit found the heart, kidney, bone, testes, and blood vessel |
What type of fixation should you use when using the schmorl reduction method | A Chromate fixative |
What are the two substances that are responsible for chromaffin reaction | 5-hydroxtyptamine and catecholamine |
What are some methods that demonstrate argentaffin cells? | Fontana masson, schmorl reducing, Gomori Burtner, Diazo, autofloursecent |
What are three types of APUD cells | stomach, duodenum & small intestine, kulchitsky cells |
Why must alcohol containing fixative be avoided? | It dissolves argentaffin granules |
What method is positive for carcinoid tumors of the appendix and small intestine and negative for bronchial carcinoids? | Diazo |
What are the bleaching solutions for melanin | Potassium Permanganate, hydrogen peroxide, performic acid and peracetic acid |
What staining methods demonstrate melanin pigment? | Gomoris Meth silver, fontana masson, ferrous iron uptake, schmorls, DOPA oxidase |
Substantia nigra is? | The portion of the brain where melanin is found |
What is gouty Tophi | Urate deposits around joints, a uric acid metabolism disorder |
Bodian stains? | Carcinoid granules brown/black |