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Chapter 15: Regulation of Gene Expression (Eukaryotic Genomes, Organization, Regulation, Evolution)

AB
activatorstimulates transcription of a specific gene
alternative RNA splicingdifferent mRNA molecules are produced from the same primary transcript
cell differentiationstructural and functional divergence of cells as they become specialized
chromatincomplex of DNA and proteins that makes up a eukaryotic chromosome
control elementnoncoding DNA that helps regulate transcription of a gene by binding with transcription factors
differential gene expressionexpression of different sets of genes by cells with the same genome
enhancerDNA segment containing multiple control elements that may be located far away from the gene it regulates
epigenetic inheritanceInheritance of traits transmitted by mechanisms not directly involving the nucleotide sequence
euchromatinopen
genomic imprintingexpression of an allele in offspring depends on whether the allele is inherited from the male or female parent
heterochromatinnontranscribed eukaryotic chromatin that is so highly compacted that it is visible with a light microscope during interphase
histoneproteins that bind to DNA to form nucleosomes in chromatin
histone acetylationattachment of acetyl groups to certain amino acids of histone proteins
micro-RNA (miRNA)directs associated proteins to degrade or prevent translation of the target mRNA.
multigene familycollection of genes with similar or identical sequences
nucleosomesegment of DNA wound around a protein core composed of two copies of each of four types of histone
oncogenepart of viral genome that triggers cancerous characteristics
p53 geneexpressed when a cell’s DNA is damaged. Its product acts as a transcription factor for several genes
proteasomerecognizes and destroys proteins tagged for elimination
proto-oncogenegene with a potential to cause cancer but that requires some alteration
pseudogeneDNA segment very similar to a real gene but which does not yield a functional product
Ras geneproduce growth signal matches membrane receptor to stimulate cell cycle
repetitive DNAnoncoding sequences present in many copies in a eukaryotic genome
repressorsuppresses the transcription of a gene
retrotransposontranscript of the retrotransposon DNA
RNA interference (RNAi)technique to silence the expression of selected genes
transcription factorbinds to DNA and stimulates transcription of specific genes
transposongenetic element that moves within a genome by means of a DNA intermediate.
tumor-suppressor genegene whose protein products inhibit cell division


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