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Blood Key Terms

AB
albuminA simple protein found in blood plasma
antibodyA protein produced in response to, and interacting specifically with, an antigen
antigenA substance that induces the formation of antibodies
coagulationThe process of clot formation
electrolyteA substance that separates into charged particles (ions) in solution; a salt. Also refers to ions in body fluids
erythrocyteA red blood cell
fibrinThe protein that forms a clot in the process of blood coagulation
fibrinogenThe inactive precursor of fibrin
formed elementsThe cellular components of blood
hemoglobinThe iron-containing pigment in red blood cells that transports oxygen
hemostasisThe stoppage of bleeding
immunityThe state of being protected against a specific disease
leukocyteA white blood cell
lymphocyteA lymphatic cell; a type of agranular leukocyte
phagocytosisThe engulfing of foreign material by white blood cells
plasmaThe liquid portion of the blood
plateletA formed element of the blood that is active in hemostasis; a thrombocyte
serumThe fraction of the plasma that remains after blood coagulation; it is the equivalent of plasma without its clotting factors
thrombocyteA blood platelet
allergenA substance that causes an allergic response
allergyHypersensititvity
anaphylactic reactionAn exaggerated allergic reaction to a foreign substance
anemiaA decrease in the number or size of red blood cells or int the amount of hemoglobin in the blood. May result from blood loss, malnutrition, a hereditary defect, environmental factors, and other causes.
aplastic anemiaAnemia caused by bone marrow failure resulting in deficient blood cell production, especially that of red cells.
autoimmune disorderA condition in which the immune system produces antibodies against an individual's own tissues
ecchymosisA collection of blood under the skin caused by leakage from small vessels
hemolysisThe rupture of red blood cells and the release of hemoglobin
hemophiliaA hereditary blood disease caused by lack of a clotting factor and resulting in abnormal bleeding
leukemiaMalignant overgrowth of immature white blood cells. May be chronic or acute; may affect bone marrow (myelogenous leukemia( or lymphoid tissue (lymphocytic leukemia)
pernicious anemiaAnemia caused by failure of the stomach to produce intrinsic factor, a substance needed for the abosrption of vitamin B12
petechiaePinpoint, flat, purplish-red spots caused by bleeding within the skin or mucous membrane
purpuraA condition characterized by hemorrhages into the skin, mucous membranes, internal organs, and other tissues.
sickle cell anemiaA hereditary anemia caused by the presence of abnormal hemoglobin, Red blood cells become sickle-shaped and interfere with normal blood flow to the tissues. Most common in Mediterranean and African populations.
splenomegalyenlargement of the spleen
thrombocytopeniaA deficiency of thrombocytes in the blood
intrinsic factorA substance produced in the stomach that aids in the absorption of vitamin B12 necessary for the manufacture of red blood cells
agglutinationThe clumping of cells or particles in the presence of specific antibodies
bilirubinA pigment derived from the breakdown of hemoglobin. It is eliminated by the liver in bile.
gamma globulinThe fraction of the blood plasma that contains antibodies
heparinA substance found throughout the body that inhibits blood coagulation; an anticoagulant
megakaryocyteA large bone marrow cell that fragments to release platelets
thrombinThe enzyme derived from prothrombin that converts fibrinogen to fibrin
stem cellA primitive bone marrow cell that gives rise to all varieties of blood cells.
agranulocytosisA conditon involving decrease in the number of granulocytes in the blood; also called granulocytopenia
erythrocytosisIncrease in the number of red cells in the blood
hematomaA localized collecton of blood, usually clotted, caused by a break in a blood vessel
lymphocytosisAn increase in the number of circulating lymphocytes. Usually a result of infection.
neutropeniaA decrease in the number of neutrophils with increased susceptibility to infection. Causes include drugs, irradiation, and infection. May be a side effect of treatment for malignancy.
pancytopeniaA decrease in all cells of the blood, as in aplastic anemia.
electrophoresisSeparation of particles in a liquid by application of an electrical field. Used to separate components of blood.
pHA scale that measures the relative acidity or alkalinity of a solution. Represents the amount of hydrogen ion in the solution.
apheresisA pprocedure in which blood is withdrawn, a portion is separated and retained, and the remainder is returned to the donor,. Apheresis may be used as a suffix with a root meaning the fraction retained, such a plasmapheresis, leukapheresis.
autologous bloodA person's own blood. May be donated in advance of surgery and transfused if needed.


Academic Assistant
R. D. Anderson Applied Technology Center

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