| A | B |
| Single circular chromosome | prokaryote |
| Multiple linear chromosomes | eukaryote |
| DNA has histone proteins wrapped around it | eukaryote |
| DNA has no histone proteins wrapped around it | prokaryote |
| Cells divide by meiosis or mitosis | eukaryote |
| Cells divide by binary fission | prokaryote |
| Lack a nucleus | prokaryote |
| Has a nucleus | eukaryote |
| Has membrane bound organelles | eukaryote |
| Has enzymes | both |
| Has DNA | both |
| Lacks membrane bound organelles | prokaryote |
| Has ribosomes | both |
| Has mitochondria | eukaryote |
| Has chloroplasts | eukaryote |
| Has endoplasmic reticulum | eukaryote |
| Has cell membrane | both |
| Has Golgi | eukaryote |
| Only some have cell walls | eukaryote |
| Has capsule | prokaryote |
| Less complex | prokaryote |
| More complex | eukaryote |
| Smaller cell | prokaryote |
| Larger cell | eukaryote |
| Cell not organized into compartments by membranes | prokaryote |
| Has nucleoid region | prokaryote |
| Cell compartmentalized by membranes | eukaryote |
| All unicellular | prokaryote |
| Unicellular or multicellular | eukaryote |
| Cell type of bacteria and archaea | prokaryote |
| cell type of fungi, plants, animals, and protists | eukaryote |
| Earliest evolutionary cell | prokaryote |
| No cytoskeleton | prokaryote |
| Some can photosynthesize | both |
| All have cell walls | prokaryote |
| May have flagella or cilia | both |