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Sterilization and Disinfection Terminology

AB
Asepsisprevents entry of infectious agents into sterile tissues
Sepsisgrowth of microorganisms in the blood and other tissues
Sterilizationthe complete removal or destruction of all viable microorganisms
Sterilantschemicals classified as sterilizing agents
Disinfectionthe destruction or removal of vegetative pathogens but not bacterial endospores
Antisepticschemicals applied to body surfaces to destroy or inhibit vegetative pathogens
Stasis and StaticGreek for “stand still”
DecontaminationThe mechanical removal of most microbes
Sanitationcleansing technique that mechanically removes microorganisms and other debris
pressure – temperature combination to achieving sterilization15 psi, which yields 121°C
Intermittent sterilizationtyndallization
PasteurizationDisinfection of Beverages
dry oven sterilization requirements150°C to 180°C for 2 to 4 hours
Desiccateddehydrated or drying out
Lyophilizationcombination of freezing ad drying
Radiationenergy emitted from atomic activities and dispersed at high velocity
Filtrationused to prepare liquids that cannot withstand heat
High-efficiency particulate air (HEPA) filtersprovide flow of decontaminated air
Halogensfluorine, bromine, chlorine, and iodine
IodophorsBetadine, Povidine, Isodine
Phenolcarbolic acid
Quaternary ammonium compoundsBenzalkonium chloride, Zephiran, and cetylpyridinium chloride
Heavy Metal CompoundsMercury, silver, gold, copper, arsenic, and zinc
Mercury tincturesthimerosal and nitro-mersol
Glutaraldehyde's sterilization requirement3 hour exposure
Ethylene oxidegas sterilant


Director of Institutional Research
Columbia International University
Columbia, SC

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