| A | B |
|---|
| Low Density Lipoproteins | increase the risk of heart disease |
| High Density Lipoproteins | decrease the risk of heart disease |
| Level less than 40 mg/dL | considered a major risk factor for heart disease |
| Levels are 150-190 | may need treatment in some patients |
| TLC | therapeutic life changes |
| Statins | inhibit manufacture of or promote breakdown of cholesterol |
| catalyst | substance that speeds up a chemical reaction w/o changing itself |
| myopathy | can be increased if taking statins with clarithromycin, niacin, amiodarone, verapamil |
| bile | manufactured by the liver;emulsifies fats |
| emulsifies | breaking down of large fat globules in intestines to smaller particles |
| bile acid resins | used to treat hyperlipidemia, pruritis associated w/biliary obst. |
| malabsorption of vitamin K | increases bleeding tendencies when taking bile acid resins |
| cholestyramine | used for biliary obst. pruritus; administer alone from other meds |
| fibric acid derivatives | third group of meds used for hyperlipidemia |
| clofibrate | stimulates liver to breakdown VLDL |
| fenofibrate | reduces VLDL stimulating breakdown triglycerides |
| gemfibrozil | increases excretion of cholesterol/reduces prod of triglycerides |
| ezetimibe | inhibits absorption of cholesterol in small intestine |
| misc antihyperlipidemic | adverse reactions n/v/d, abd pain, flushing of skin, itching or tingling |
| hyperlipidemia | elevated LDL and decreased HDL |
| myopathy | congenitalor acquired muscle disease, marked clinically by focal or diffuse muscle weakness |
| primary hypertension | linked to no known cause; cannot be cured but can be controlled |
| secondary hypertension | there is a reason for the hypertension such as another disease process |
| salt sensitive | when a person with more than minimum amount of salt can develop hypertension |
| diuretics/beta adrenergic blocker | first pharmacological choice |
| ACEIs | angiotension converting enzyme inhibitors |
| endogenous | made by the body |
| aldosterone | increases water in the body |
| Calcium Channel Blockers | nerve impulses |
| Angiotension II Receptor Antagonist | sites in vascular smooth muscle and adrenal gland |
| Nitroprusside | given IV for hypertensive emergency |
| ACEIs and ACEIIs contraindicated in | renal impairment, salt or volume depleted, angioedema |
| nitrates | relax smooth muscle of blood vessels |
| calcium channel blockers | slow conduction velocity; depress contractility; dilate coronary arteries and arterioles |
| antianginal drugs | relieve pain; prevent angina; treat chronic stable angina pectoris |
| verapamil | control hypertension and cardiac arrhythmias |
| Ca Channel Blockers adverse reactions | CNS-h/a, etc; hypotension; flushing; rash |
| nitrates contraindicated in | severe anemia; close angle glaucoma; postural hypotension, etc |
