| A | B |
| Haiti | The Caribbean island nation that won their independence from France in 1803. (283) |
| Missouri River | Lewis & Clark struggled against the current of this river on the first leg of their journey. (284) |
| Zebulon Pike | This army lieutenant led two expeditions to explore the Mississippi River valley. The highest peak in Colorado bears his name. (285) |
| Louisiana Territory | The vast area that stretched from the Mississippi River west to the Rocky Mountains. (283) |
| secede | Federalists in New England plotted to ___________, and start a new nation called "The Northern Confederacy" because they were unhappy about the Louisiana Purchase. (285) |
| William Clark | Meriwether Lewis chose him to co-lead the expedition. He drew the first accurate maps of the American West. (284) |
| Sacagawea | This Shoshone Indian served as a valuable guide and translator to the Lewis & Clark expedition. (284) |
| Thomas Jefferson | This President quickly made the Louisiana Purchase in 1803, doubling America's size. (283) |
| France | The nation America purchased the Louisiana Territory from in 1803. (283) |
| Meriwether Lewis | President Jefferson chose him to lead a journey to explore the American West. (284) |