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cardiovascular system

blood

AB
plasmaliquid portion of blood
functions of bloodtransport, homeostasis
hematologystudy of blood
average volume of blood5 liters
components of bloodcellular(formed elements), plasma
formed elements45%
plasma55%
plasmacontains H20, hormones,wastes,proteins,etc
formed elementscontains RBC, WBC, platelets
RBCerythrocytes
erythrocytes RBCcontain hemoglobin
RBClack nuclei
RBCaverage life span 120 days
erythropoiesisRBC production
RBC production( adults)red bone marrow
RBC production(fetusesyolk sac, liver, spleen
erythropoietinhormone that stimulates RBC production
WBCleukocytes
granulocytesneutophils, eosinophils, basophils
agranulocytesmonocytes, lymphocytes
neutrophilsmost common, 50-70%, phagocytosis, fight infection
eosinophils1-4%, allergic reactions
basophilsless 1%,release heparin(inhibit clotting), histamine (itis)
monocytes3-8%, largest, phagocytosis
lymphocytes20-30%, large nucleus, antibodies, immunity
WBCaverage 5000-10,000
leukemiaabnormal production of leukocytes, elevated
plateletsthrombocytes
plateletsfragments of cells
plateletsblood clotting
hemocytoblastall blood cells formed from this, cell producer
anemialow Hct or Hb, cause decrease in O2 to tissues
sickle-cellabnormal shaped RBC
polycythemiaelevated Hct with normal blood volume
Hemophiliainadequate production of clotting factors
Trypanosoma gambienseAfrican sleeping sickness
Plasmodiumcause Malaria
RBC4-6 million/ml, 25 trillion in adult
platelet130,000-360,000
RBCno nucleus
hematocritobtains number of RBC and WBC in sample of blood
lymphocytesimmunity Tcells, antibodies Bcells
plasma proteinsalbumin (osmotic press.), fibrinogen(clotting), globulins(immunity)
RH postiveyou have antigen for it
RH negativeyou don't have antigen for it
erythroblastosis fetalis+ baby and - mother
hemostasisstoppage of bleeding
thromboplastinaids in clotting
clotting sequenceprothrombin ,thrombin,fibrinogen,fibrin
anticlotting factorsheparin=blocks thrombin production
anticlottingwarfrin=vitamin k inhibitor
anticlottingplasminogen=lyses clot
anticlottingprostocyclin=blocks thromboxane(platelet formation)
thrombosisfixed clot
embolismfreely drifting clot, to brain,heart,lungs
arteriosclerosisfatty accumulations in arteries
plaminogenbreaks up blood clots
streptokinaseclot buster drug
antigenson surface of RBC
antibodiesprotein in plasma
agglutinationclumping of RBC when testing compatibility

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