| A | B |
| William Becknell | the "Father of the Santa Fe Trail" |
| Stephen Austin | the man who took over for his father when he died leading families into Texas |
| Antonio Lopez de Santa Anna | the army officer who had taken over Mexico's government |
| James Gadsden | the US minister to Mexico who negotiated the purchase of a strip of land south of the Mexican Session in present-day Arizona |
| John O'Sullivan | the newspaper editor who coined the term "Manifest Destiny" |
| Joseph Walker | the man hired by Benjamin Bonneville to find a trail to California |
| John Fremont | the man sent by the US government to survey and map the Oregon Trail |
| Brigham Young | the man who took over for the founder of the Mormon Church |
| James K. Polk | the man who became President after John Tyler |
| John Sutter | the man upon whose land gold was first discovered in California |