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BIO 102 Evolution 2/20/13

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Evolution Via Gene TransferBacterial reproduction usually involves just dividing in two; no other bacteria is required. But every once in a while a bacterium acquires genes from somewhere else. When it does, it’s not too picky about which genes it gets.
PlasmidsOne of the 3 ways that bacteria can acquire new DNA.Tiny little critters that live inside bacteria. Just a small circle of DNA, just a few genes. 1) Genes for replicating 2) Genes for spreading from one bacterium to another (via conjugation) 3) Genes for other stuff (like antibiotic resistance)
ConjunctionThe process in which two bacteria join and DNA is passed from one to the next. This process is controlled by a small circle of DNA living within the bacterium, called a plasmid, and it’s the way that the plasmid spreads from one bacterium to another.
TransformationThe process whereby a bacterial cell picks up DNA from its environment and incorporates it into its own genome.
TransductionThe process whereby genes are carried from one bacterium to another in a bacterial virus. Occasionally, a virus particle being assembled before leaving the host cell accidentally gets filled with bacterial DNA instead of viral DNA. When that virus particle latches onto a new bacterium, it injects that bacterium with the foreign bacterial DNA, which may then be incorporated into the bacterium’s genome.
Overuse of Antibiotics Help Select for Resistant BacteriaPrescriptions for antibiotics given out when they are not needed (viral infection) and given out too often Antibiotics given to animals
Misuse of Antibiotics Help Select for Resistant BacteriaNot taking the entire prescription Self-medicating with antibiotics Antibiotics given to animals that are not sick
Partial ResistanceBacteria may evolve complete resistance to a particular antibiotic by first passing through a stage of partial immunity. Partially resistant bacteria can survive a concentration of the antibiotic sufficient to kill susceptible bacteria but will succumb to a greater concentration. Additional mutations can then make them more completely resistant
Vector Borne DiseasesRequire a vector for their transmission, such as a mosquito
West Nile VirusAttacks the central nervous system. Transmitted by Culex mosquitoes that breed in stagnant water. Primary host is birds – humans are dead end. (Zoonotic) Local emergence of the virus is seen primarily when the local conditions favor mosquito breeding
Vector Borne EmergenceEmergence of these diseases is regulated by vector abundance, dependent on local ecology/climate. Global warming is changing where mosquitoes can live
FomiteAny inanimate object or substance capable of carrying infectious organisms. Can get it from people, bugs, etc.



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