A | B |
Mitochondrion, cytoplasmic membrane of | Aerobic Respiration |
Mitochondrion Outer membrane: | 50/50 lipid/protein and Mitochonrial porin |
Mitochondrion Intermembrane space | Continuous with cytosol |
Mitochondrion Inner membrane | 75% protein, highly impermeable, Cristae, and Studded with ATP synthase |
Glycolysis | Is a catabolic process; Occurs in the cytosol; One molecule of glucose is partially oxidized to smaller molecules to generate ATP and reduced NADH + H+ |
1 Glucose yields: | 2 pyruvates, 2 ATPs, 2 NADH + 2H+ |
Allosteric mechanisms control enzymatic | turn glycolysis “up” or “down” |
Hexokinase inhibited | by glucose 6-phosphate |
Pyruvate kinase inhibited | by ATP |
Phosphofructokinase-1 regulated by | ATP/AMP, fructose 2,6-bisphosphate |
Phosphofructokinase-1 Substrates | ATP (ADP + Pi) and Fructose 6-phosphate |