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Cell Bio 4100 Biomembranes Part 1

AB
Properties of Lipid Bilayer Hydrophobic core acts aspermeability barrier
Properties of Lipid Bilayer Hydrophobic and van der Waals interactionsstabilize bilayers
Lipid bilayersspontaneously seal
Membrane CompositionLipids, Proteins, Carbohydrates
LipidsFatty acid—Triglyceride—Phosphoglyceride
Lipid molecules rotate and movelaterally
Fluidity~rate of movement of lipid molecules
Lipid CompositionAffects Membranes
Desaturasesenzymes that desaturate single carbon-carbon bonds
Phospholipases and acyltransferases—“reshuffle” and transfer unsaturated fatty acids
Leaflets of Bilayer areAsymmetric
Organization of Lipids isNot Random
Lipid raftsareas of reduced fluidity
Membrane ProteinsIntegral proteins, Peripheral proteins, Lipid-anchored proteins
Integral ProteinsPossess at least one trans-membrane domain
Parts of integral protein on outside or inside ofmembrane are usually globular and hydrophilic


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