A | B |
Citric Acid Cycle: Pyruvate + CoASH + NAD+ → | AcetylCoA + CO2 + NADH (transition step) |
Citric Acid Cycle: AcetylCoA + 2 H2O + FAD + 3 NAD+→ | 2 CO2 + FADH2 + 3 NADH + GTP |
Fatty Acid converted to | fatty acyl CoA in cytosol |
Fatty acid covalently transferred to | carnitine; transported across inner mitochondrial membrane; reattached to CoASH |
Carbons from fatty acyl CoA are transferred | in twos to acetyl CoA |
For every two carbons transferred to CoASH: | FADH2 and NADH |
High energy e- stored in NADH and FADH2 are passed down to | a series of molecular complexes by alternating reduction/oxidation reactions |
Reducing Power At the End of Citric Acid Cycle | 2 NADH from glycolysis |
“Prosthetic Groups” | Capable of being reduced and oxidized and Electron carriers |
Proton Motive Force | Combination of ΔpH and Δ charge across membrane and Drives synthesis of ATP in ATP synthase and Chemiosmotic hypothesis |
ATP Synthase | F0 and F1 domains, F0 domain embedded in inner mitochondrial membrane, and F1 domain protrudes from membrane into matrix |
Complex IV Cytochrome c Oxidase | e- transferred from reduced cytochrome c |
Complex I NADH-CoQ Reductase | 2 e- transferred from NADH |
Complex II Succinate-CoQ Reductase | 2 e- transferred from FADH2 |
Complex III CoQH2-Cytochrome c Reductase | 2 e- transferred from CoQH2 to cytochrome c |