| A | B |
|---|
| Destination of RER Proteins | Secreted to exterior, Membrane proteins, Some proteins stay in ER, Some proteins are transported to and stay in Golgi, Some proteins are exported to lysosomes |
| Anteretrograde | outward: moving from cis to trans direction |
| Retrograde: | moving trans to cis direction |
| Parent organelle | donor |
| Target organelle | recipient |
| Cargo | luminal and membrane protein |
| SNARE proteins: | Integral membrane proteins facilitate fusion of membranes |
| Bud: | protrusion or curvature of membrane (forming vesicle) |
| Trafficking Steps | GTP switches control initiation of vesicle formation, Assembly of coat proteins – “gathering of cargo,” |
| GTPase Switch Proteins | ARF protein and SAR 1 protein |
| Membrane proteins targeted for vesicle transport | are “recognized” by coat proteins |
