A | B |
Anticoagulants | Category of agents which inhibit clots from forming. |
Antiplatelets | Category of agents which prevent platelets from sticking together. |
Thrombolytics | Category of agents which break down clots already formed. |
Heparin | Anticoagulant agent which inhibits the action of Thrombin and prolongs clotting time. |
Partial thromboplastin time | Blood test to determine the effectiveness of Heparin. |
Protamine Sulfate | Antidote for overdose of Heparin. |
Low Molecular Weight Heparin | Anticoagulant agent used preventatively which is less able to inactivate thrombin and has less risk for bleeding. |
Warfarin | Oral anticoagulant which inhibits hepatic synthesis of Vitamin K and affects clotting factors. |
International Normalized Ratio | Blood test used to measure the effectiveness of Warfarin. |
Phytonidione (Vit K) | Antidote for overdose of Warfarin. |
Side effects of Anticoagulant drugs | Ecchymosis, bruising, tarry stools, hemorrhage. |
HDL (high density lipids) | Category of lipoprotein which removes cholesterol from the blood. |
LDL (Low density lipids) | Category of lipoprotein which increases cholesterol in the body. |
Desirable Cholesterol level | < 200 mg/dL |
Desirable HDL | > 50 mg/dL |
Bile-acid sequestrants | Antihyperlipidemic agent which binds to bile acids in the intestine. |
Fibrates | Antihyperlipidemic agent which reduces production of triglycerides in the liver. |
Nicotinic Acid (Vit B3) | Antihyperlipidemic agent which decreases production of cholesterol in the liver. |
SE of Nicotinic Acid | flushing of skin, headaches, hepatotoxicity |
Cholesterol Absorption Inhibitors | Antihyperlipidemic agent which inhibits cholesterol absorption in the small intestines. |
Statins | Antihyperlipidemic agent which inhibits an enzyme (HMG-CoA) essential for cholesterol synthesis. |
SE of Statin drugs | muscle pain, rhabdomyolysis, cataract formation |